Publications

2008

2007

  • Chirifu, M., Hayashi, C., Nakamura, T. et al. 2007 Sep. Crystal structure of the IL-15-IL-15Ra complex, a cytokine-receptor unit presented in trans. Nature Immunology. 8(9):1001–7.
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  • Yasui, N., Nogi, T., Kitao, T., Nakano, Y., Hattori, M., and Takagi, J. 2007 Jun 12. Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors. Proc. Natl. Acad. Sci. USA. 104(24):9988-93.
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  • Latham, C.F., Hu, S.H., Gee, C.L. et al. 2007 Jun 1. Crystallization and preliminary X-ray diffraction of the Munc18c-syntaxin4 1-29 complex. Acta Crystallograph Sect F Struct Biol Cryst Commun. 63(Pt 6):524-8.
  • Kothe, M., Kohls, D., Low, S., et al. 2007 May 22. Structure of the catalytic domain of human polo-like kinase 1. Biochemistry. 46(20):5960-71.

  • Hu, S.H., Latham, C.F., Gee, C.L., James, D.E., and Martin, J.L. 2007 May 22. Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins. Proc. Natl. Acad. Sci. USA. 104(21):8773-8.
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2006

  • Ottesen, E.A., Hong, J.W., Quake, S.R., and Leadbetter, J.R. 2006 Dec 1. Microfluidic digital PCR enables multigene analysis of individual environmental bacteria. Science. 314(5804):1464-7.

  • Warren, L., Bryder, D., Weissman, I.L., and Quake, S.R. 2006 Nov 21.Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR. Proc. Natl. Acad. Sci. USA. 103(47):17807-12.

  • English, C.M., Adkins, M.W., Carson, J.J., Churchill, M.E., and Tyler J.K. 2006 Nov 3. Structural basis for the histone chaperone activity of Asf1. Cell. 127(3):495-508.

  • Stevens, J., Blixt, O., Tumpey, T.M., Taubenberger, J.K., Paulson, J.C., and Wilson, I.A. 2006 Apr 21. Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus. Science. 312(5772):404-10.
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  • Rowland, P., Blaney, F.E., Smyth, M.G., et al. 2006 Mar 17. Crystal structure of human cytochrome P450 2D6. J. Biol. Chem. 281(11):7614-22.

2005

  • Lee C.C., Sui, G., Elizarov, A. et al. 2005 Dec 16. Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics. Science. 310(5755):1793-1796.

  • Segelke B. 2005 Apr. Macromolecular crystallization with microfluidic free-interface diffusion. Expert Rev. Proteomics. 2(2):165-72.
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2004

  • Hansen, C.L., Sommer, M.O., and Quake S.R. 2004 Oct 5. Systematic investigation of protein phase behavior with a microfluidic formulator. Proc. Natl. Acad. Sci. USA. 101(40):14431-6.
  • Xiao, T., Takagi, J., Coller, B.S., Wang, J.H., and Springer T.A. 2004 Nov 4. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 432(7013):59-67.
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2003

  • Liu, J., Hansen, C., and Quake, S.R. 2003 Sep 15. Solving the 'world-to-chip' interface problem with a microfluidic matrix. Analytical Chemistry. 75(18): 4718-4723.
  • Wheeler, A.R., Throndset, W.R., Whelan, R.J., et al. 2003 Jul 15. Microfluidic device for single-cell analysis. Analytical Chemistry. 75(14):3581-3586.
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2002

  • Hansen, C.L., Skordalakes, E., Berger, J.M., and Quake S.R. 2002 Dec 24. A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion. Proc. Natl. Acad. Sci. USA. 99(26):16531-6.

  • Thorsen, T., Maerkl, S.J., and Quake, S.R. 2002 Oct 18. Microfluidic large-scale integration. Science. 298(5593):580-584.

2001

  • Chou, H.P., Unger, M.A., and Quake, S.R. 2001 Dec. A microfabricated rotary pump. Biomedical Microdevices. 3(4): 323-330.

2000

  • Quake, S.R. and Scherer, A. 2000 Nov 24. From micro- to nanofabrication with soft materials. Science. 290(5496):1536-1540.

  • Unger, M.A., Chou, H.P., Thorsen, T., Scherer, A., and Quake, S.R. 2000 Apr 7. Monolithic microfabricated valves and pumps by multilayer soft lithography. Science. 288(5463):113-116.

1999

  • Fu, A.Y., Spence, C., Scherer, A., Arnold, F.H., and Quake, S.R. 1999 Nov. A microfabricated fluorescence-activated cell sorter. Nature Biotechnology 17(11):1109-1111.
  • Chou, H.P., Spence, C., Scherer, A., and Quake, S. 1999 Jan 5. A microfabricated device for sizing and sorting DNA molecules. Proc. Natl. Acad. Sci. USA. 96(1):11-13.



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