"We analyzed RNA from single Oct4-MO-injected and control embryos and focused on genes that were under-expressed in Oct4 knockdown."
"Oct4 may serve not only as a link between the germ cell and embryonic developmental programs, but also as a switch from a post-transcriptionally-regulated program to one that depends on the transcriptional network."
COPY NUMBER VARIATION
Accurate and easy methods to genotype copy number variants using nanofluidics and PCR.
Recent experiments demonstrate the versatility of Dynamic Arrays in measuring gene copy number variations with unparalleled throughput and sensitivity.
Find out more at qPCR 2009,
San Diego, CA USA
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New Products
THE NEXT GENERATION DIGITAL ARRAY HAS ARRIVED!
48 Samples x 770 Partitions
Experience higher throughput while achieving highly sensitive detection for applications such as
• Copy number variation studies
• Mutation detection
• Sample prep for next gen sequencing
• Cancer research
INTRODUCING THE FLUIDIGM EP1 SYSTEM
Exceptionally high throughput and data quality, with TaqMan® assays and Fluidigm dynamic arrays.
Accelerate
• 96 samples x 96 SNPs
• 9216 reactions per chip
• Your TaqMan® primers & probes
Enable
• Fast, simple workflow
• Greater than 99% call rates
• 200,000 or more genotypes per day
New Applications
NEXT GEN SEQUENCING SAMPLE PREP USING THE SlingShot™ KIT BY FLUIDIGM
We don’t make next generation sequencers. We make them better.
New SlingShot kits allow you to achieve the ideal DNA library concentration for your next gen sequencing — without the need for titration runs, reference samples, or mass bias calibrators.
RESCUE those archived samples!
Use 1,000-fold less sample material than conventional methods
Accelerate
• Only 3.5 hours from digital PCR
to DNA quantification
• Minimal hands-on time
• Maximum confidence in sequencing results
Enable
• Fast, simple workflow
• Outstanding data quality
• Minimal liquid transfer steps
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DIGITAL PCR
Recently published article provides insight into the underlying digital PCR technology.
Fetal Aneuploidy detection from cell-free DNA and maternal plasma RNA using Digital PCR.
SNP GENOTYPING
Genetic signature for fish populations may be used to identify unknown-origin fish.
CRITFC characterizes fish genetic variations in the Columbia river to better understand diversity, adaptation and dispersal in natural salmon populations.
Events
April 18 - 22, 2009
AACR 2009
Denver, CO
May 23 - 26, 2009
ESHG 2009
Vienna, Austria
In The News
• February 19, 2009
• February 2, 2009
EP1 System Delivers Enhanced Work Flow and Great Data Quality
• January 8, 2009
EP1 System Delivers High Data Quality with Best-In-Class Workflow Efficiency
• December 16, 2008
California’s Stem Cell Agency Invests in Cell Culture Integrated Fluidic Circuit System
• December 1, 2008
About this newsletter The IFC Application Hotspot is your quick source for the latest news on Fluidigm integrated fluidic circuits (IFCs). In each edition we share new products, applications, and customer advances using revolutionary IFC technology. Address comments to the Fluidigm newsletter editor.
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