Products & Services Instruments Biomark HD

Biomark HD 

No more compromising for quality. 

With the Biomark™ HD system, you get reliable production-scale throughput and excellent sensitivity, with a wide variety of sample types and chemistry choices to accommodate the most genomic applications. Now you can run entire projects from research to validation to routine screening on a single system with the flexibility you want and the consistency you need. 

Large image of Fluidigm's Biomark HD instrument

Technology

Our revolutionary integrated fluidic circuits (IFCs) empower life science research by automating molecular biology in nanoliter volumes. This means using less sample and reagent, and a single  microfluidic device, to achieve the high-quality, consistent results your work depends on.

Workflow

1

Prime

Prime the Dynamic Array IFC to prepare it for sample transfer.

2

Transfer

Pipet samples and primer-probe sets into the designated inlets on the IFC.

3

Load

Load the IFC on the controller, which prepares the reactions.

4

Run

Place the IFC into Biomark for thermal cycling and end-popint or real-time fluorescence detection.

5

Analyze

View and analyze color-coded expression heat maps, allele maps and cluster plots for single or multipule runs with our analysis software.

Biomark and EP1 Software

The latest software for the Biomark™ HD, Biomark and EP1™ systems. Package includes software for data collection, real-time PCR analysis, genotyping, digital PCR and melting curve analysis. To inst...

Biomark Pathogen Detection Software

Software that analyzes qPCR Ct data from Biomark HD to detect and identify mutations. For installation and instructions please reference the Biomark Pathogen Detection Software Quick Reference Guid...

CopyCount-CNV Software

The cloud-based software analyzes raw fluorescence qPCR data from Biomark™ HD to determine absolute quantification and provide DNA copy number results. Applications include transgene copy number, e...

GO Immuno-Oncology Workbench

GO Immuno-Oncology Workbench is designed to further analyze primary data obtained with the Advanta™ IO Gene Expression Assay. GO Immuno-Oncology Workbench enables users to analyze large cohorts, di...

IFC Controllers Software (HX, MX, RX, and WX)

The latest software for IFC Controllers HX, MX, RX and WX. To install, follow the instructions in the Update Software and Scripts section of the relevant IFC Controller User Guide (HX/MX, PN 680001...

Singular Analysis Toolset Software

An innovative, open-source solution for analyzing and visualizing data, the Singular™ Analysis Toolset offers powerful methods for identifying gene expression and mutation patterns at the single-ce...

Software

Get the precise results your research deserves!

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Support

A critical success factor when adopting high-performance technology is acquiring the proficiency and support necessary to accelerate your research and discovery initiatives. Fluidigm PRO Services are a comprehensive portfolio of solutions to help you maximize your investment, scale up productivity and empower your laboratory with greater access to professional resources.

Products

Related products that will help you make the most of this instrument: 

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Resources

Specifications

Instrument (Part Number BMKHD-BMKHD) 

Dimensions 

Depth

75 cm (29.5 in)

Width

75 cm (29.5 in)

Height

100 cm (39.4 in)

Weight

140 kg (308 lb)

Thermal Control

Peltier-based, 4–99 ºC

Heating ramp rate

Up to 5.5 ºC/sec

Cooling ramp rate

Up to 5.5 ºC/sec

Detection

CCD camera; 9M pixel, 12 μm x 12 μm pixel size

Fluorescence excitation

475 nm, 530 nm, 575 nm

Fluorescence emission

525 nm, 570 nm, 630 nm

Power requirements

100–230 VAC, 50/60 Hz, 300 W Fluidigm provides a region-specific power cord for the Biomark HD system.

Instrument Control Computer 

Computation

Intel® Core™ i3-2120, 3.30 GHz

Memory

2GB

Storage

500 GB HDD

Ports

4 USB 1GB/sec Ethernet

Operating System

Microsoft® Windows® 10 IoT Enterprise 2016 LTSB (32 bit)

Monitor

LCD flat panel

Accessories

Keyboard and mouse

Supported IFCs 

Gene expression

48.48 Dynamic Array™ IFC 96.96 Dynamic Array IFC 192.24 Gene Expression IFC Flex Six™ Gene Expression IFC

Genotyping

48.48 Dynamic Array IFC 96.96 Dynamic Array IFC 192.24 Genotyping IFC Flex Six Genotyping IFC

Digital PCR

qdPCR 37K™ IFC 48.770 Digital Array™ IFC 12.765 Digital Array IFC

Software 

Data Collection

Biomark HD Data Collection software

Analysis

Real-Time PCR Analysis software, SNP Genotyping Analysis software, Digital PCR Analysis software, Melt Curve Analysis software

Work Environment (indoor use only) 

Temperature

15–30 ºC (59–86 ºF)

Humidity

20%–80% relative humidity, non-condensing

Altitude

Not to exceed 2,000 m (6,560 ft) above sea level

Unless explicitly and expressly stated otherwise, all Fluidigm products are provided for Research Use Only, not for use in diagnostic procedures. For more information see www.fluidigm.com/legal/notices