Products & Services Technologies Imaging Mass Cytometry

Imaging Mass Cytometry

Gain unprecedented insights from highly multiplexed single-cell spatial biology

Imaging Mass Cytometry™ (IMC™) is a vital tool that allows researchers to gain an appreciation of the role of heterogeneity in cell function and assess complex phenotypes and tumor-immune interactions in the tissue and tumor microenvironment. Gain a deeper understanding of the spatial environment to answer important translational and clinical research questions in the context of disease.

When speed matters, get faster answers for cohort analysis and clinical studies with the second-generation Hyperion+™ Imaging System.

 

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Workflow

1

Design

Design panels using pathologist-verified Maxpar® antibodies conjugated to metal tags.

2

Stain

Stain tissues (FFPE or frozen) using familiar IHC protocols.

3

Image

Image up to 40 protein markers at single-cell resolution using the Hyperion™ Imaging System.

4

Analyze

Analyze images in minutes using the MCD™ Viewer and easily export for secondary analysis.

Using the Hyperion Imaging System, you can visualize the complex spatial biology of the tissue microenvironment with Imaging Mass Cytometry.

 

  • Single-cell resolution: allows accurate and quantifiable phenotyping and cell function assessment

  • No autofluorescence: reliable results when working with highly autofluorescent tissues like lung, gut, brain and skin

  • No time-consuming cyclic protocols: high-plex protein detection from formalin-fixed, paraffin-embedded or frozen tissue sections

  • Proven: hundreds of hands-on users and more than 130 peer-review published references

Expert insight on the transformation of precision medicine

Olivier Elemento, PhD
Professor, Physiology and Biophysics, Weill Cornell Medicine
Director, Englander Institute for Precision Medicine

Oliver Elemento shares his expert insight on the transformation of precision medicine. In this short video, Elemento describes why artificial intelligence, high-throughput sequencing and Imaging Mass Cytometry are becoming increasingly critical tools for personalizing treatments and improving patient outcomes.


Publications

Keep current with how Imaging Mass Cytometry (IMC) is used to gain deep spatial insights – see articles, news, bibliographies, tips and more. Check out the IMC Trending Topics and Publications.

IMC TRENDING TOPICS & PUBLICATIONS

VIEW ALL Publications

JOIN US

Join the hundreds of researchers globally who are using Imaging Mass Cytometry to phenotype the tissue microenvironment, stratify samples and discover biomarkers to gain therapeutic insights that address significant translational and clinical research questions.

See more than 130 publications

Events

Join us for one of our upcoming events or watch on demand.

View All Events

Apr 08 - Apr 13

Location

AACR Annual Meeting 2022 (American Association for Cancer Research) in New Orleans, LA

Mar 27 - Mar 30

Location

ABRF (Association of Biomolecular Resource Facilities) in Palm Springs, CA

Mar 23

Webinar

Sample Tracking in Genomic Workflows Using the Biomark ™ X System and New Analysis Pipeline Software

Jun 21 - Jun 23

Location

Sequencing to Function: Analysis and Applications for the Future (SFA²F) in Santa Fe, NM

Oct 12 - Oct 14

Location

NERLSCD 2022 (Northeast Regional Laboratory Staff & Core Directors) in Rochester, NY

Sep 16 - Sep 18

Location

GLIIFCA XXXI (Great Lakes International Imaging and Flow Cytometry Association) in Indianapolis, IN

Apr 27

Virtual

Scientist in the Spotlight - Receptor Occupancy - Gerd Bringeland and Sonia Gavasso "Monitoring antibody therapies – bead based receptor occupancy quantitation in mass cytometry"

Jun 03 - Jun 07

Location

CYTO 2022 (International Society for Advancement of Cytometry ) in Philadelphia, PA

Jun 13 - Jun 16

Location

CROPS 2022 - Huntsville, AL

Jun 21

Virtual

Mega Insights with Microfluidics 2022: Roundtable Discussion on Biomark™ X

Sep 21 - Sep 22

Location

WACD 2022 (Western Association of Core Directors) at the California NanoSystems Institute at UC Los Angeles

Sep 19 - Sep 20

Location

Forum LABO in Lyon, France

Mar 25

Virtual

GEN: Single-Cell Immune Profiling Can Help Resolve Tumor Microenvironment Complexities

Apr 25

Webinar

CAP Today: Innovations in Immune Profiling for Clinical Research

Apr 08

Virtual

Scientist in the Spotlight - Nicole Strittmater "Multimodal imaging strategies to increase our understanding of drug delivery"

May 18

Virtual

Scientist in the Spotlight in collaboration with the EACR - Bernd Bodenmiller "Multiscale Analysis of Tumor Ecosystems Towards Precision Medicine"

Jun 07

Virtual

Scientist in the Spotlight - Ilaria Michelozzi High-dimensional functional phenotyping of preclinical human CAR T cells using mass cytometry

May 24

Webinar

Save the Date: Igniting Insight in Immuno-Oncology CyTOF® Flow Cytometry Virtual Summit

Jun 14

Webinar

Cytometry Powered by Time-of-Flight: Igniting Insight into Immuno-Oncology: CyTOF Summit, Tuesday, June 14

Jun 15

Webinar

Cytometry Powered by Time-of-Flight: Igniting Insight into Immuno-Oncology: IMC Forum, Wednesday, June 15

Nov 13 - Nov 14

Physical-and-Virtual

SITC 2021 (Society for Immunotherapy of Cancer) in Washington, DC

Nov 01 - Nov 03

Virtual

Frontiers in Cancer Science 2021

Gerard Evan

Jesús Gil Valles

Thomas Gajewski

Apr 14

Virtual

Scientist in the Spotlight - Simon Cabello and Julie Vendrell-"Theranostic, prognostic and diagnostic uses of a flexible Solid Tumor NGS library prep assay in a university hospital

Nov 04

Virtual

Scientist in the Spotlight with Corinne Ramos from ImaBiotech

Corinne Ramos

Apr 25

Webinar

IMC Forum 2022: Current Methods and Future Views for Effective Cell Segmentation in High-plex Imaging

Jul 12

Webinar

Imaging Mass Cytometry™ Master Class: IMC Image Basics and Image Processing with MCD Viewer

Lindsy Rapkin, PhD

Jul 20 - Jul 22

Location

FlowCytometry UK in Birmingham, UK

Sep 21 - Sep 24

Location

ESCCA (European Society for Clinical Cell Analysis) in Bellfast, UK

Sep 21 - Sep 22

Location

International Spatial Biology Congress in The Hague, The Netherlands

Oct 21

Virtual

IMC Summit: Uncovering Spatial Biology

Chris Linthwaite

Melissa Davis, PhD

Bernd Bodenmiller, PhD

Unless explicitly and expressly stated otherwise, all products are provided for Research Use Only, not for use in diagnostic procedures. Find more information here.