Cell-ID™ Cisplatin-194Pt is a monoisotopic preparation of cisplatin containing the 194Pt isotope. Cisplatin is a stain that binds covalently to cellular proteins, and labels cells with compromised cell membranes to a greater extent than live cells. Cell-ID Cisplatin-194Pt therefore specifically identifies dead cells if cells are incubated prior to fixation, or it identifies total cells if cells are incubated following cell fixation and permeabilization. Because cisplatin binds covalently to protein, its labeling remains strong through subsequent cell handling steps used in downstream mass cytometry cell staining protocols.
Cell-ID™ Cisplatin-194Pt—100 µL