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Anti-Human p53 (7F5)-143Nd—50 Tests

Tumor protein p53 (TP53) is a 53 kDa tetramer protein that prevents cancer formation and functions as a tumor suppressor. This protein is localized to the nucleus when activated and can be up-regulated by genotoxic or other cellular stresses. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. It is a transcriptional activator of genes that inhibit growth and/or invasion, cell cycle checkpoint after irradiation, DNA repair, apoptotic induction, signal transduction, and cell adhesion.

  • Species:
    Human
  • Clone:
    7F5
  • Target:
    p53
  • Tag:
    143Nd

 

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