Aldehyde dehydrogenase (ALDH) is a tetrameric enzyme that oxidizes aldehydes to carboxylic acids and enables cells to resist oxidative stress. ALDH is expressed in the majority of mammalian tissues. There are multiple isoforms of ALDH; class I (cytosolic), class II (mitochondrial) and class III (microsomal). ALDH has been implicated as a cancer stem cell marker. Cells with high ALDH levels have demonstrated enhanced tumorigenicity in multiple cancer cell types. In clinical studies, high ALDH activity predicted poor survival in breast and ovarian cancer.
Anti-Human ALDH (44/ALDH)-147Sm—100 Tests