CD127, also known as the IL-7 receptor α chain or IL-7α, is a 60–90 kDa type I transmembrane glycoprotein. It is a heterodimer consisting of IL-7Rα (CD127) and a common-γ chain receptor (CD132), which is shared with various cytokines including IL-2,-4,-9,-13,-15 and -21. CD127 is expressed on immature B through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. It can be a useful marker for identifying memory and effector T cells and differentiation of Treg and conventional T cells.
Anti-Human CD127/IL-7Ra (A019D5)-149Sm—100 Tests