Syk is a cytoplasmic 72 kDa nonreceptor tyrosine kinase that plays an important role in intracellular signal transduction in hematopoietic cells. Syk is widely expressed in hematopoietic cells, including B lymphocytes, immature (CD4, CD8 double-negative and CD8 double-positive) thymocytes, myeloid cells, epithelial cell lines and normal breast tissue. The Syk kinase couples the activated immunoreceptors to downstream signaling events that mediate cellular proliferation, differentiation and phagocytosis.
Anti-Human Syk (4D10.2)-149Sm—25 µg
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Species:Human
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Clone:4D10.2
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Target:Syk
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Tag:149Sm
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