Anti-Human Syk (4D10.2)-149Sm—25 µg

Syk is a cytoplasmic 72 kDa nonreceptor tyrosine kinase that plays an important role in intracellular signal transduction in hematopoietic cells. Syk is widely expressed in hematopoietic cells, including B lymphocytes, immature (CD4, CD8 double-negative and CD8 double-positive) thymocytes, myeloid cells, epithelial cell lines and normal breast tissue. The Syk kinase couples the activated immunoreceptors to downstream signaling events that mediate cellular proliferation, differentiation and phagocytosis.

• Species:
  Human
• Clone:
  4D10.2
• Target:
  Syk
• Tag:
  149Sm