CD169, also known as sialoadhesin (Sn), sheep erythrocyte receptor (SER) or Siglec-1, is a type I transmembrane glycoprotein containing a single Ig-like V-type domain and 16 Ig-like C2-type domains. CD169 binds a number of sialylated molecules including the mannose receptor, MGL1, MUC1, PSGL-1 and different glycoforms of CD43. CD169 is expressed on macrophages and dendritic cells in peripheral blood, lymph nodes and spleen in humans. By its affinity to α2, 3-linked sialic acid, it is involved in macrophage binding to different cell types such as granulocytes, monocytes and NK, B and T cells.
Anti-Human CD169 (7-239)-158Gd—100 Tests