Anti-Mouse CD23 (B3B4)-159Tb—100 Tests

CD23, the low-affinity receptor for immunoglobulin E (IgE), is a type II transmembrane protein and a member of the C-type lectin family. In mice, CD23 is detected on the surface of B cells, follicular dendritic cells, and the gut epithelium, and has been widely used in combination with other markers to differentiate between subsets during B cell maturation. It has been proposed that CD23 plays an important role in the negative feedback of IgE production in vivo. This is based on increased IgE levels in CD23-deficient mice and decreased IgE levels in mice overexpressing CD23.

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    100 Tests


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