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Anti-Human CD370/CLEC9a (8F9)-161Dy—100 Tests

CLEC9a (C-type lectin domain family 9, member A) is also known as CD370 or DNGR1 (Dendritic cell natural killer lectin group receptor 1). It is a type II transmembrane protein consisting of a single extracellular C-type lectin domain (CTLD) and an intracellular cytoplasmic tail with immunoreceptor tyrosine-based activation motif (ITAM). CLEC9a is selectively expressed on plasmacytoid dendritic cells and CD8+ myeloid dendritic cells. CLEC9a acts as a receptor for necrotic cells and regulates the cross-presentation of dead cell-associated antigens in a Syk-dependent manner.

  • Species:
    Human
  • Clone:
    8F9
  • Target:
    CD370/CLEC9A/DNGR1
  • Tag:
    161Dy

 

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