CD1d is a type I transmembrane protein, structurally homologous to class I MHC molecules. It consists of a glycosylated type I transmembrane α chain (43–49 kDa), which forms a heterodimer with β2-microglobulin. CD1d is a member of the CD1 family of molecules in the immunoglobulin superfamily. CD1 molecules fall into two groups. Group 1 includes CD1a, CD1b, and CD1c molecules. Group 2 includes CD1d molecules and their homologs. CD1d is expressed on cortical thymocytes, B cells, dendritic cells, monocytes, and some nonlymphoid cells including intestinal epithelial cells, hepatocytes and keratinocytes. CD1d has been implicated in lipid antigen presentation to CD1d-restricted NKT cells.
Anti-Human CD1d (51.1)-162Dy—100 Tests