CD196, also known as CC-chemokine receptor type 6 (CCR6), is expressed on immature dendritic cells, B lymphocytes and memory T cells. CCR6-positive cells and CCR6 ligand CCL20 have been detected in numerous organs, especially the secondary lymphoid organ. CD196 can mediate the arrest of T cells and has been reported to be highly expressed on T cells resident in both normal and psoriatic skin. CCR6 and/or CCL20 have also been implicated in the pathogenesis of various inflammatory autoimmune diseases, playing a role in the recruitment of Th17 cells.
Anti-CD196/CCR6 (G034E3)-163Dy—25 µg
-
Species:Cross
-
Clone:G034E3
-
Target:CD196 (CCR6)
-
Tag:163Dy
-
Sample Type:Frozen (FF)
Browse more products
-
Applications:
-
System:
-
Product Type:
-
Category: