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Anti-Mouse CD31/PECAM-1 (390)-165Ho—100 Tests

CD31, or platelet endothelial cell adhesion molecule-1 (PECAM-1), is a 130–140 kDa member of the immunoglobulin gene superfamily. It is expressed at high levels at the lateral borders of endothelial cells and at a lower density on the surface of hematopoietic cells including T lymphocytes. By establishing homophilic interactions between endothelium- and leukocyte-expressed CD31, this protein has been shown to facilitate leukocyte transendothelial migration. CD31 deficiency in mice leads to elevated disease severity in experimental models of T cell-mediated inflammation including experimental autoimmune encephalomyelitis (EAE).

  • Species:
    Mouse
  • Clone:
    390
  • Target:
    CD31/PECAM-1
  • Tag:
    165Ho

 

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