Anti-pH2AX [S139] (N1-431)-165Ho

The H2AX histone belongs to the H2A histone family, whose members are components of nucleosomal histone octamers. Double-stranded breaks in DNA caused by replication errors, apoptosis or other physiological processes (including immunoglobulin and TCR gene recombinations) and DNA damage caused by ionizing radiation, UV light or cytotoxic agents lead to phosphorylation of H2AX on serine 139. Phosphorylated H2AX promotes DNA repair and maintains genomic stability and thus helps prevent oncogenic transformations.

  • Species:
    Human, Mouse
  • Clone:
  • Target:
    pH2AX [S139]
  • Tag:
  • Sample Type:


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