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Anti-Mouse CD49b (HMa2)-170Er—100 Tests

CD49b, also known as integrin α2, is a 150 kDa subunit that binds noncovalently with integrin β1 (CD29) to form the receptor VLA-2. VLA-2 is a receptor for collagen and laminin. VLA-2 is expressed by some CD4+ T cells, intraepithelial lymphocytes (IEL), NK cells, platelets, and epithelial cells. Evidence suggests that the collagen-binding VLA-2 can be a major regulator of T cell activation. It has been shown that co-expression of CD49b and LAG-3 identifies human and mouse T regulatory type I cells.

  • Species:
    Mouse
  • Clone:
    HMa2
  • Target:
    CD49b
  • Tag:
    170Er

 

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