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Anti-Mouse CD169/Siglec-1 (3D6.112)-170Er-—100 Tests

CD169, also known as Siglec-1 and sialoadhesin (Sn), is a 175–185 kDa type I lectin containing 17 immunoglobulin (Ig) domains (one variable domain and 16 constant domains). Acting as a macrophage-restricted cell surface receptor, CD169 preferentially binds to alpha 2,3-linked sialic acid residues and is expressed on stromal macrophages in many tissues, particularly in lymph nodes and bone marrow, and on marginal metallophilic macrophages in the spleen. CD169 mediates sialic acid-dependent binding of macrophages to granulocytes, monocytes, NK cells, B cells and T cells.

  • Species:
    Mouse
  • Clone:
    3D6.112
  • Target:
    CD169/Siglec-1
  • Tag:
    170Er

 

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