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Anti-Mouse CD86 (GL1)-172Yb—100 Tests

CD86 is an 80 kDa immunoglobulin superfamily member. It is also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

  • Species:
    Mouse
  • Clone:
    GL1
  • Target:
    CD86
  • Tag:
    172Yb

 

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