The HLy9.1.25 monoclonal antibody binds specifically to CD229, a 100–120 kDa single-pass type I membrane glycoprotein also known as signaling lymphocyte activation molecule family member 3 (SLAMF3), lymphocyte antigen 9 (Ly9), or T lymphocyte surface antigen Ly-9. CD229 is expressed on T cells, B cells, NK cells, and thymocytes. CD229 is thought to play a role in adhesive interactions between T and B cells via a homophilic binding interaction. It has been observed that CD229 localizes to the immunological synapse during T cell activation.
Anti-Human CD229 (HLy9.1.25)-174Yb—100 Tests