1282 results found in Gene Expression

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  The Haematopoietic Stem Cell Lab

  Developing stem cell treatments at Cambridge Institute for Medical Research …

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  Understanding Central Immune System Cells

  Mario Roederer discusses his NIH research characterizing HIV-treatment immunology …

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  Streamlined microRNA Expression Profiling

  Simplify the complexity with our new single-cell miRNA expression profiling workflow …

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  Creating Consensus on Bioethics

  Peers debate the ethics of cellular biotechnology at BEINGS 2015 International Summit …

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  Know the Players

  Combinatorial, single-cell approaches to explore the complexity of biologic systems …

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  What’s New for C1 Applications on Script Hub

  View the growing list of community-developed apps for single-cell biology …

• Publications

  A subpopulation of itch‐sensing neurons marked by Ret and somatostatin expression

  Itch, the unpleasant sensation that elicits a desire to scratch, is mediated by specific subtypes of cutaneous sensory neuron. …

• Publications

  DGCR8 is essential for tumor progression following PTEN loss in the prostate

  In human prostate cancer, the microRNA biogenesis machinery increases with prostate cancer progression …

• Publications

  Is idiopathic hirsutism (IH) really idiopathic? mRNA expressions of skin steroidogenic enzymes in women with IH

  Hirsutism results from hyperandrogenemia and/or exaggerated androgen responsiveness. …

• Publications

  Longitudinal analysis of sarcoidosis blood transcriptomic signatures and disease outcomes

  Previously, we demonstrated concordance in differentially expressed genes in sarcoidosis blood and lung, implicating shared dysfunction of specific immune pathways. …

• Publications

  Cell adhesion molecules and cathelicidin in mice model of hypersensitivity pneumonitis

  Hypersensitivity pneumonitis (HP) is a complex clinical condition involving a cascade of immune reactions triggered and sustained by lung injury due to repeated inhalations of fine particles inhaled to airways. …

• Publications

  A mouse GM-CSF receptor antibody attenuates neutrophilia in mice exposed to cigarette smoke

  We investigated the role of granulocyte-macrophage colony-stimulating factor (GM-CSF) in a subchronic exposure model of cigarette smoke (CS)-induced inflammation using antibodies directed against GM-CSF or the GM-CSF receptor (GM-CSFR) α-chain. …

• Publications

  Model-Based Characterization of Inflammatory Gene Expression Patterns of Activated Macrophages

  Macrophages are cells with remarkable plasticity. …

• Publications

  Robust Inference of Cell-to-Cell Expression Variations from Single- and K-Cell Profiling

  Quantifying heterogeneity in gene expression among single cells can reveal information inaccessible to cell-population averaged measurements. …

• Publications

  Type I IFNs Regulate Inflammation, Vasculopathy, and Fibrosis in Chronic Cutaneous Graft-versus-Host Disease

  Type I IFNs play a critical role in the immune response to viral infection and may also drive autoimmunity through modulation of monocyte maturation and promotion of autoreactive lymphocyte survival. …

• Publications

  High purity galacto-oligosaccharides (GOS) enhance specific Bifidobacterium species and their metabolic activity in the mouse gut microbiome

  Prebiotics are selectively fermented ingredients that result in specific changes in the composition and/or activity of the gastrointestinal microbiota, thus conferring benefit(s) upon the host health. …

• Publications

  Dok1 and Dok2 Proteins Regulate Cell Cycle in Hematopoietic Stem and Progenitor Cells

  Dok1 and Dok2 proteins play a crucial role in myeloid cell proliferation as demonstrated by Dok1 and Dok2 gene inactivation, which induces a myeloproliferative disease in aging mice. In this study, we show that Dok1/Dok2 deficiency affects myeloproliferation even at a young age. …

• Publications

  Limited effects of preterm birth and the first enteral nutrition on cerebellum morphology and gene expression in piglets

  Preterm pigs show many signs of immaturity that are characteristic of preterm infants. …

• Publications

  Invariant NKT Cell Activation Induces Late Preterm Birth That Is Attenuated by Rosiglitazone

  Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality worldwide. …

• Publications

  A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors

  Thymic T-cell development is initiated from bone marrow-derived multi-potent thymus seeding progenitors (TSPs). …