292 results found in Imaging Mass Cytometry

• consumable

  Imaging Mass Cytometry

  Reagents for deep interrogation of tissues and tumors …

• media

  Seminar | Uncovering Cellular Networks

  Analysis of Tissue Ecosystems in Health and Disease by Imaging Mass Cytometry …

• media

  Seminar | Advancing Translational and Clinical Research

  Imaging Mass Cytometry to Characterize the Tumor Immune Microenvironment …

• consumable

  Anti-Human Smooth Muscle Actin (1A4)-141Pr—25 µg

  Alpha smooth muscle actin is a 42 kDa cytoskeletal protein expressed in smooth muscle cells of blood vessels, myofibroblasts and myoepithelial cells. …

  Product #: 3141017D

• consumable

  Anti-Human p53 (DO-7)-143Nd—25 µg

  p53 is a 53 kDa protein that operates as a tumor suppressor and helps regulate hundreds of genes in response to various types of stress. …

  Product #: 3143026D

• consumable

  Anti-Vimentin (D21H3)-143Nd—25 µg

  Vimentins are class-III intermediate filaments found in various nonepithelial cells, especially mesenchymal cells. …

  Product #: 3143027D

• consumable

  Anti-pTyrosine (P-Tyr-100)-144Nd—25 µg

  Tyr100 recognizes phosphorylated tyrosine residues in all proteins. An increase in total cellular phosphotyrosine levels indicates a shift in the balance of tyrosine protein kinases and phosphases. …

  Product #: 3144024D

• consumable

  Anti-Human T-bet/TBX21 (D6N8B)-145Nd—25 µg

  T-bet (Tbx21) is a transcription factor bearing a T-box DNA-binding domain. It is considered a master-regulator of the Th1 CD4+ T cell subset. …

  Product #: 3145015D

• consumable

  Anti-p4E-BP1 [T37/T46] (236B4)-149Sm—25 µg

  4E-BP1, also known as PHAS-1, is a member of the 4E-BP (eIF4E-binding protein) family of translational repressors, which also includes 4E-BP2 and 4E-BP3. …

  Product #: 3149023D

• consumable

  Anti-Human Syk (4D10.2)-149Sm—25 µg

  Syk is a cytoplasmic 72 kDa nonreceptor tyrosine kinase that plays an important role in intracellular signal transduction in hematopoietic cells. …

  Product #: 3149024D

• consumable

  Anti-Human CD15 (W6D3)-149Sm—25 µg

  CD15, also known as LewisX, 3-FAL and SSEA-1, is a carbohydrate adhesion molecule, 3-fucosyl-N-acetyllactosamine (3-FAL). …

  Product #: 3149026D

• consumable

  Anti-Human PD-L1 (E1L3N)-150Nd—25 µg

  PD-L1, also known as CD274, is one of the ligands for programmed death 1 (PD-1), and is an immune-inhibitory receptor belonging to the CD28/cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) family. …

  Product #: 3150031D

• consumable

  Anti-Human CD45 (D9M8I)-152Sm—25 µg

  CD45, also known as leukocyte common antigen (LCA) and T200, is expressed on the plasma membrane of all hematopoietic cells except mature red blood cells and platelets. …

  Product #: 3152018D

• consumable

  Anti-Human IDO (D5J4E)-155Gd—25 µg

  Indoleamine-2,3-dioxygenase (IDO) is an intracellular enzyme that catalayzes the degradation of tryptophan to kynurenines. IDO is considered to be an immunosuppressive molecule that limits T cell proliferation and activation through trytophan starvation of T cells. …

  Product #: 3155017D

• consumable

  Anti-Human CD68 (KP1)-159Tb—25 µg

  CD68, also known as macrosialin, is predominantly an intracellular protein found in the late endosomal compartment but can also be detected in small amounts on the surface of myeloid-derived cells. …

  Product #: 3159035D

• consumable

  Anti-Human CD20 (H1)-161Dy—25 µg

  CD20, also known as B1 and Bp35, is a transmembrane spanning protein expressed on pre-B cells, immature and mature B cells, and some follicular dendritic cells. …

  Product #: 3161029D

• consumable

  Anti-Human Pan-Keratin (C11)-162Dy—25 µg

  Keratins (cytokeratins) are a group of intermediate filament proteins that are mainly expressed in epithelial cells. …

  Product #: 3162033D

• consumable

  Anti-Human CD223/LAG-3 (D2G40)-153Eu—25 µg

  Lymphocyte activation gene 3 (LAG-3), also known as CD223, shares homology with CD4, and LAG-3 binding to MHC class II is thought to contribute to the negative regulation of T cell activation. …

  Product #: 3153028D

• consumable

  Anti-Human FoxP3 (236A/E7)-155Gd—25 µg

  Foxp3, a member of the Fox protein family of transcriptional regulators, is a master regulator of the regulatory T (Treg) CD4+ T cell subset. …

  Product #: 3155016D

• consumable

  Anti-Human Vista (D1L2G)-160Gd—25 µg

  VISTA, also known as B7-H5, is a 55–65 kDa transmembrane protein belonging to the Ig superfamily primarily expressed by myeloid cells. It is a negative checkpoint control protein that regulates T cell activation and immune responses. …

  Product #: 3160025D