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348 results found in Imaging Mass Cytometry

  • brochure

  • brochure

  • consumable

    Anti-CD19 (6OMP31)-142Nd—25 µg

    CD19, also known as B4, is expressed on B cells, B cell progenitors and follicular dendritic cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. …

    Product #: 3142014D

  • consumable

    Anti-Human/Mouse CD44 (IM7)-153Eu—25 µg

    CD44 is involved in cell-to-cell interactions, adhesion, homing and migration as well as being a receptor for hyaluronic acid. CD44 is expressed on a number of cell types including leukocytes, endothelial cells, hepatocytes and mesenchymal cells and has been reported to be a marker for memory cell subsets. …

    Product #: 3153029D

  • consumable

    Anti-Human B7-H4 (H74)-166Er—25 µg

    B7-H4 is a costimulatory protein reported to function as a negative regulator of T cell-mediated immunity. B7-H4 is expressed on activated T cells, B cells, monocytes and dendritic cells. …

    Product #: 3166030D

  • consumable

    Anti-EGFR (D38B1)-142Nd—25 µg

    Epidermal growth factor receptor (EGFR), also known as ErbB-1 and HER1 in humans, regulates cell growth and differentiation. EGFR is expressed or highly expressed in a variety of human tumors of epithelial origin. …

    Product #: 3142013D

  • consumable

    Anti-Human pH2AX [S139] (N1-431)-165Ho—25 µg

    The H2AX histone belongs to the H2A histone family, whose members are components of nucleosomal histone octamers. Phosphorylation of H2AX on serine 139 promotes DNA repair and maintains genomic stability. …

    Product #: 3165036D

  • consumable

    Anti-pERK1/2 [T202/Y204] (D13.14.4E)-171Yb—25 µg

    ERK1 and ERK2, also known as p44 and p42 MAPKs, are similar (85% sequence identity) members of the mitogen-activated protein kinase (MAPK) family of serine/threonine protein kinases. ERK1/2 signaling is important in the cellular response to a wide range of stimuli including growth factors, cytokines and mitogens. …

    Product #: 3171021D

  • consumable

    Anti-Human CD31 (EPR3094)-151Eu—25 µg

    CD31 is expressed by endothelial cells, monocytes, granulocytes, platelets and a small subset of T cells. It plays a role in wound healing, angiogenesis, removal of aged neutrophils and cellular migration in an inflammatory situation. …

    Product #: 3151025D

  • consumable

    Anti-Human PD-L2 (D7U8C)-172Yb—25 µg

    PD-L2 is a ligand for PD-1 that is involved in costimulation or suppression of T cell proliferation. It is mainly expressed by subpopulations of myeloid-lineage cells including dendritic cells and monocytes/macrophages. …

    Product #: 3172031D

  • consumable

    Anti-Human CD25 (EPR6452)-175Lu—25 µg

    CD25 is a T cell growth factor receptor for IL-2. It is expressed on regulatory and activated T cells, activated B cells, macrophages and monocytes. …

    Product #: 3175036D

  • consumable

    Anti-Human CD194/CCR4 (L291H4)-149Sm—25 µg

    CD194, also known as CCR4, belongs to the G protein-coupled receptor family. It is expressed on stimulated and unstimulated T and B cells, basophils, monocytes, and NK cells. …

    Product #: 3149030D

  • consumable

    Anti-pHistone H3 [Ser28] (HTA28)-176Yb—25 µg

    Histone H3 is phosphorylated on threonine 3, serine 10, serine 28 and threonine 32 when cells enter mitosis. Phosphorylation at serine 10 or 28 occurs in association with the induction of immediate-early genes and is part of the nucleosomal response downstream of the activation of the ERK1/2 or p38 MAPK pathways. …

    Product #: 3176024D

  • consumable

    Anti-CD33 (Polyclonal)-145Nd—25 µg

    CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It binds sialic acids and contains intracellular tyrosine-based inhibition motifs (ITIMs), which are implicated in inhibition of cellular activity. …

    Product #: 3145017D

  • consumable

    Anti-Human CD163 (EDHu-1)-147Sm—25 µg

    CD163 is expressed by monocytes and macrophages. It plays a role in clearing hemoglobin and regulating cytokine production by macrophages. …

    Product #: 3147021D

  • consumable

    Anti-Human CD73 (EPR6115)-158Gd—25 µg

    CD73 is expressed on bone marrow-derived mesenchymal stem cells and subsets of follicular dendritic cells, epithelial cells, endothelial cells and T and B lymphocytes. CD73 may mediate costimulatory signals in T cell activation and adhesion of lymphocytes to endothelium. …

    Product #: 3158031D

  • consumable

    Anti-Human CD196/CCR6 (Polyclonal)-163Dy—25 µg

    CCR6 is expressed on immature dendritic cells, B lymphocytes, memory T cells, monocytes, macrophages and neutrophils. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells. CCR6 and/or its ligand, CCL20, have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease. …

    Product #: 3163029D

  • consumable

    Anti-Human VEGF (G153-694)-163Dy—25 µg

    VEGF is a highly specific mitogen for vascular endothelial cells and induces angiogenesis and permeabilization of blood vessels. It is secreted by pituitary cells, monocytes/macrophages, smooth muscle cells and keratinocytes. …

    Product #: 3163028D

  • consumable

    Anti-SOX9 (EPR14335)-147Sm—25 µg

    SOX9 is a transcription factor associated with the testis-determining factor sex-determining region Y. It is expressed mainly in adult tissues and also in fetal testis and skeletal tissue. …

    Product #: 3147022D

  • consumable

    Anti-Human Granzyme B (EPR20129-217)-167Er—25 µg

    Granzyme B is a serine protease abundantly stored in the granules of cytotoxic T lymphocytes (CTL) and natural killer cells. …

    Product #: 3167021D