366 results found in Single-Cell Genomics
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article
Tumor Profiling at Single-Cell Resolution
Shyam Prabhakar explores signatures of patient survival and EMT in colorectal tumors …
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Publications
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system
C1
The first automated solution for single-cell genomics, now capable of even more …
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article
The Single-Cell Analysis Technologist
Burroughs Wellcome Fund honors Charles Gawad’s genomics mission for pediatric biology …
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Publications
Integrative single-cell transcriptomics reveals molecular networks defining neuronal maturation during postnatal neurogenesis
In mammalian hippocampus, new neurons are continuously produced from neural stem cells throughout life. …
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Publications
RNA-guided endonuclease provides a therapeutic strategy to cure latent herpesviridae infection
Latent viral infection is a persistent cause of human disease. Although standard antiviral therapies can suppress active viral replication, no existing treatment can effectively eradicate latent infection and therefore a cure is lacking for many prevalent viral diseases. …
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Publications
A multi-scale approach reveals that NF-κB cRel enforces a B-cell decision to divide
Understanding the functions of multi-cellular organs in terms of the molecular networks within each cell is an important step in the quest to predict phenotype from genotype. …
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product insert
C1 Reagent Kit for Preamplification Product Insert
This kit is used to facilitate the capture of cells and performing preamplification on single cells or for targeted gene expression analysis.
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system
Polaris
Seamless integration of cell biology and molecular analysis at the single-cell level …
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media
A Novel, Multifactorial Approach for hiPSC Differentiation and Reprogramming Using an Automated Cell Culture System
A major challenge in the stem cell field is to define the optimal condition for cell expansion, differentiation and reprogramming.
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Publications
Effect of cryopreservation on delineation of immune cell subpopulations in tumor specimens as determinated by multiparametric single cell mass cytometry analysis
Comprehensive understanding of cellular immune subsets involved in regulation of tumor progression is central to the development of cancer immunotherapies. …
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Publications
Single-Cell Multiomics: Multiple Measurements from Single Cells
Single-cell sequencing provides information that is not confounded by genotypic or phenotypic heterogeneity of bulk samples. …
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technical note
Cell Sorting Directly to the C1 IFC Application Note
Sorting directly into the C1 IFC cell inlet can be a very effective strategy for obtaining a rare subpopulation of cells with high purity and viability from a larger population.
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technical note
Single-Cell Genomics in Immunology Technical Note
Gene expression profiling at the single-cell level is possible with both targeted and whole transcriptome approaches, such as qPCR and mRNA sequencing (mRNA seq).
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article
What’s New for C1 Applications on Script Hub
View the growing list of community-developed apps for single-cell biology …
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article
Exploring Diversity with Single-Cell Clarity
Confidently scale your cell atlas or lineage study with the new C1 medium-cell HT IFC …
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article
Amplify Your Productivity
With more than 1,000 publications and counting, Biomark is a rising star in PCR …
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Protocol
C1 System for mRNA Seq Protocol
Using C1 to Generate Single-Cell cDNA Libraries for mRNA Sequencing
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Publications
Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation
Differentiation of lymphocytes is frequently accompanied by cell cycle changes, interplay that is of central importance for immunity but is still incompletely understood. …
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Publications
Live single-cell laser tag
The ability to conduct image-based, non-invasive cell tagging, independent of genetic engineering, is key to cell biology applications. …