Anti-Mouse I-A/I-E (M5/114.15.2)-174Yb—100 Tests

The M5/114.15.2 monoclonal antibody binds to the mouse major histocompatibility complex class II proteins I-A and I-E (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). They are expressed on antigen-presenting cells including B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2b, H-2d, H-2q, H-2p, H-2r and H-2u haplotypes but not from mice carrying the H-2s or H-2f haplotypes. I-A/I-E are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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    100 Tests


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