135 results found in Hyperion Imaging System
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Publications
Mass synaptometry: High-dimensional multi parametric assay for single synapses
Synaptic alterations, especially presynaptic changes, are cardinal features of neurodegenerative diseases and strongly correlate with cognitive decline. …
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Publications
Mass Spectrometry Imaging and Integration with Other Imaging Modalities for Greater Molecular Understanding of Biological Tissues
Over the last two decades, mass spectrometry imaging (MSI) has been increasingly employed to investigate the spatial distribution of a wide variety of molecules in complex biological samples. …
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User Guide
Hyperion Imaging System User Guide
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Site Requirements
Hyperion Imaging System Site Requirements Guide
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specification
Hyperion Imaging System Specification Sheet
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Quick Reference
Hyperion Imaging System Site Quick Reference
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Quick Reference
Hyperion Imaging System Site Requirements Quick Reference
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Publications
Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a disease of unmet medical need. …
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Publications
Multiplex protein detection on circulating tumor cells from liquid biopsies using imaging mass cytometry
Molecular analysis of circulating and disseminated tumor cells (CTCs/DTCs) has great potential as a means for continuous evaluation of prognosis and treatment efficacy in near-real time through minimally invasive liquid biopsies. …
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Publications
Simultaneous Multiplexed Imaging of mRNA and Proteins with Subcellular Resolution in Breast Cancer Tissue Samples by Mass Cytometry
To build comprehensive models of cellular states and interactions in normal and diseased tissue, genetic and proteomic information must be extracted with single-cell and spatial resolution. …
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Publications
Immune activation underlies a sustained clinical response to Yttrium-90 radioembolisation in hepatocellular carcinoma
Yttrium-90 (Y90)-radioembolisation (RE) significantly regresses locally advanced hepatocellular carcinoma and delays disease progression. …
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Publications
Opposing Roles of Dendritic Cell Subsets in Experimental GN
Dendritic cells (DCs) are thought to form a dendritic network across barrier surfaces and throughout organs, including the kidney, to perform an important sentinel function. …
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Protocol
Imaging Mass Cytometry Staining for FFPE Sections Protocol
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User Guide
Mass Cytometry Instruments Safety Guide
Safety Information for Mass Cytometry Systems
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Publications
Clonal diversity revealed by morphoproteomic and copy number profiles of single prostate cancer cells at diagnosis
Tumor heterogeneity is prevalent in both treatment-naïve and end-stage metastatic castration-resistant prostate cancer (PCa), and may contribute to the broad range of clinical presentation, treatment response, and disease progression. …
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Publications
Automatic single cell segmentation on highly multiplexed tissue images
The combination of mass cytometry and immunohistochemistry (IHC) enables new histopathological imaging methods in which dozens of proteins and protein modifications can be visualized simultaneously in a single tissue section. …
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Publications
histoCAT: analysis of cell phenotypes and interactions in multiplex image cytometry data
Single-cell, spatially resolved omics analysis of tissues is poised to transform biomedical research and clinical practice. …
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tds
Anti-Arginase-1 164Dy
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tds
Anti-Cleaved Caspase 3 (5A1E)-172Yb
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tds
Anti-Cytokeratin 7 (RCK105)-164Dy