Biomark HD, EP1, Access Array, C1, Callisto, Juno and Polaris Systems and IFC Controllers Patent Notice and Limited License November 30, 2015

Biomark™ HD System

Fluidigm Product Patent Notice
The Fluidigm Biomark HD System, methods for reading the Dynamic Array IFCs and Digital Array IFCs using the Biomark HD System, and/or the manufacture of the Biomark HD System may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,307,802, 7,588,672, 7,604,965, 7,666,361, 7,691,333, 7,704,735, 7,749,737, 7,906,072, 8,048,378, 8,512,640, 8,721,968, 8,926,905 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

EP1™ System

Fluidigm Product Patent Notice
The Fluidigm EP1 System, methods for thermal cycling and/or reading the Dynamic Array IFCs and Digital Array IFCs using the EP1 System, and/or the manufacture of the EP1 System may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,604,965, 7,666,361, 7,691,333, 7,749,737 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

Access Array™ System

Fluidigm Product Patent Notice
The Fluidigm Access Array System, methods for controlling and/or thermal cycling the Access Array IFC using the Access Array System, and/or the manufacture of the Access Array System may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,040,338, 7,216,671, 7,479,186, 7,704,735, 7,766,055, 8,105,553, 8,105,824, 8,389,960 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

IFC Controller AX

Fluidigm Product Patent Notice
The Fluidigm IFC Controller AX, methods for controlling the Access Array IFC using the IFC Controller AX, and/or the manufacture of the IFC Controller AX may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,040,338, 7,216,671, 7,479,186, 7,704,735, 7,766,055, 8,105,553, 8,105,824, 8,389,960 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

IFC Controller HX

Fluidigm Product Patent Notice
The Fluidigm IFC Controller HX, methods for controlling the 96.96 Dynamic Array IFCs and Flex Six IFC using the IFC Controller HX, and/or the manufacture of the IFC Controller HX may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,040,338, 7,216,671, 7,479,186, 7,704,735, 7,766,055, 8,104,497, 8,105,553, 8,105,824, 8,389,960, 8,616,227 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

IFC Controller MX

Fluidigm Product Patent Notice
The Fluidigm IFC Controller MX, methods for controlling the 48.48 Dynamic Array IFCs, 12.765 Digital Array IFC, 48.77 Digital Array IFC and qd37K Digital Array IFC using the IFC Controller MX, and/or the manufacture of the IFC Controller MX may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,040,338, 7,216,671, 7,479,186, 7,604,965, 7,666,361, 7,691,333, 7,704,735, 7,749,737, 7,766,055, 8,104,497, 8,105,553, 8,105,824, 8,157,434, 8,163,492, 8,389,960 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

IFC Controller RX

Fluidigm Product Patent Notice
The Fluidigm IFC Controller RX, methods for controlling the 192.24 Dynamic Array IFC using the IFC Controller RX, and/or the manufacture of the IFC Controller RX may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,040,338, 7,216,671, 7,479,186, 7,704,735, 7,766,055, 8,104,497, 8,105,553, 8,105,824, 8,389,960 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

IFC Controller WX

Fluidigm Product Patent Notice
The Fluidigm IFC Controller WX, methods for controlling the FR48.48 Dynamic Array IFC using the IFC Controller WX, and/or the manufacture of the IFC Controller WX may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,040,338, 7,216,671, 7,479,186, 7,704,735, 7,766,055, 8,105,553, 8,105,824 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

C1™ System

Fluidigm Product Patent Notice
The Fluidigm C1 System, methods for controlling and/or reading the C1 IFCs using the C1 System, and/or the manufacture of the C1 System may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 6,767,706, 7,040,338, 7,216,671, 7,479,186, 7,704,735, 7,766,055, 8,105,553, 8,105,824, 8,257,666, 8,273,574, 8,389,960, 8,455,258, 8,673,645, 8,871,446 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

Callisto™ System

Fluidigm Product Patent Notice
The Fluidigm Callisto System, methods for controlling and/or reading the Callisto IFC using the Callisto System, and/or the manufacture of the Callisto System may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,040,338, 7,216,671, 7,479,186, 7,704,735, 7,766,055, 8,105,553, 8,105,824, 8,389,960 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

Juno™ System

Fluidigm Product Patent Notice
The Fluidigm Juno System, methods for controlling and/or reading the Access Array IFC, Dynamic Array IFCs, Digital Array IFCs, and Juno 96.96 Preamp IFC using the Juno System, and/or the manufacture of the Juno System may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,040,338, 7,216,671, 7,479,186, 7,604,965, 7,666,361, 7,691,333, 7,704,735, 7,749,737, 7,7660,55, 8,104,497, 8,105,553, 8,105,824, 8,157,434, 8,163,492, 8,389,960, 8,616,227 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

Polaris™ System

Fluidigm Product Patent Notice
The Fluidigm Polaris System, methods for controlling and/or reading the Polaris Single Cell Dosing mRNA Seq IFC using the Polaris System, and/or the manufacture of the Polaris System may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,040,338, 7,216,671, 7,307,802, 7,479,186, 7,588,672, 7,704,735, 7,766,055, 7,906,072, 8,048,378, 8,105,553, 8,105,824, 8,273,574, 8,389,960, 8,455,258, 8,512,640, 8,673,645, 8,926,905 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

CyTOF, CyTOF 2, and Helios Systems Patent Notice November 30, 2015

CyTOF®, CyTOF 2, and Helios™ Systems

Fluidigm Product Patent Notice

The CyTOF®, CyTOF® 2, and Helios™ Systems and their use may be covered by one of more of the following U.S. Patents owned or licensed by Fluidigm Corporation and/or its affiliates: U.S. Patent Nos. 7,135,296, 7,479,630, 7,767,407, 8,003,312, 8,101,368, 8,236,511, 8,354,242, 8,963,076, 9,176,137, 9,952,134 and additional foreign patents and pending patent applications.

For Research Use Only. Not for use in diagnostic procedures.

Singular Analysis Toolset

Singular Analysis Toolset License Agreement

The Singular Analysis Toolset is a shared-source, proprietary data analysis resource for Fluidigm customers interested in analyzing or developing software for single-cell DNA sequencing and gene expression data generated on Fluidigm technology. It is comprised of unsupported software development resources, including R-scripts, documentation, and reference data. 

Registered users of the Singular Analysis Toolset may use the code contained in this file in accordance with the terms set forth in sections 1 through 9 below. You may register to use the toolset at the following address: http://www.fluidigm.com/singular-analysis-toolset-request.html. Unregistered users or users whose registration has not been confirmed with a receipt at the aforementioned website have no rights or permission to use this code.

1 Use of the code in source and binary forms, with or without modification is permitted solely in accordance with section 3 below.

2 Redistribution of the code in source and binary forms, with or without modification is permitted only to employees and agents of entities named as registered users of the Singular Analysis Toolset. Redistribution, whether in source or binary form must include this license statement.

3 Any use must be in conjunction with a Fluidigm product. Any use with a Fluidigm product may also be in conjunction with data from any source, including products from other vendors. In any case, the code may not be used in conjunction with any product similar to the Fluidigm Biomark™ Real-Time System that is made by another entity.

4 Any redistribution and use shall be in accordance with the laws and export regulations of the United States of America. Under no circumstances shall code be distributed to or used by persons listed on the Denied Persons List maintained by the United States Department of Commerce, or be distributed to or used or executed in a country listed on the Export Control List, List of Extensively Embargoed Countries, or List of Targeted Sanctions Countries Territories maintained by the United States Department of Commerce; appropriate measures shall be taken to ensure that recipients will also refrain from distribution to such parties.

5 Fluidigm will not provide, and is not responsible for providing any end-user support.

6 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF NON-INFRINGEMENT, MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.

7 Fluidigm Corporation grants a limited license to the sample data set(s) provided herein for the purposes of evaluation of the Singular Analysis Toolset and for training on its use. Other uses not expressly permitted are prohibited.

8 This license, and all matters relating to use of the Singular Analysis Toolset shall be governed by and interpreted in accordance with the law of the State of California except for its choice of law rules. For any disputes arising out of this Agreement, the parties consent to the personal and exclusive jurisdiction of, and venue in, the state and federal courts within San Mateo County, California.

9 This license constitutes the entire agreement between you and Fluidigm Corporation. This license may only be amended or supplemented by a writing that refers explicitly to this Agreement and that is signed by duly authorized representatives of both parties.

Copyright © 2015 Fluidigm Corporation. All rights reserved.  

Access Array, Dynamic Array, Digital Array, C1, Callisto, Juno and Polaris Integrated Fluidic Circuit (IFC) Patent Notice and Limited License November 30, 2015

Limited License and Disclaimer for Fluidigm Systems with Fluidigm IFCs

Except as expressly set forth herein, no right to copy, modify, distribute, make derivative works of, publicly display, make, have made, offer to sell, sell, use, or import a Fluidigm system or any other product is conveyed or implied with the purchase of a Fluidigm system (including the Access Array System, Biomark System, C1 System, Callisto System, EP1 System, FC1 Cycler, IFC Controllers, Juno System, Polaris System, or any components thereof), and Access Array IFCs, Dynamic Array IFCs and Digital Array IFCs, IFC controller, software, reagents, or any other items provided hereunder.  This limited license permits only the use by the buyer of the particular product(s), in accordance with the written instructions provided therewith in the User Guide, that the buyer purchases from Fluidigm or its authorized representative(s).  Except to the extent expressly approved in writing by Fluidigm or its authorized representative(s), the purchase of any Fluidigm product(s) does not by itself convey or imply the right to use such product(s) in combination with any other product(s).  In particular, (i) no right to make, have made, or distribute other instruments, IFCs, software, or reagents is conveyed or implied by the purchase of the Fluidigm system, (ii) no right to make, have made, import, distribute, or use a Fluidigm system is conveyed or implied by the purchase of any other instruments, software, reagents, or IFCs from Fluidigm or otherwise, and (iii) except as expressly provided in the User Guide, the buyer may not use and no right is conveyed to use the Fluidigm system in combination with instruments, software, reagents, or IFCs unless all component parts have been purchased from Fluidigm or its authorized representative(s).  For example, purchase of a Fluidigm system and/or an IFC controller conveys no right or license to patents covering the Fluidigm IFCs or their manufacture, such as U.S. Patent Nos. 6,408,878, 6,645,432, 6,719,868, 6,793,753, 6,929,030, 7,323,143, 7,601,270, 7,867,763, 8,002,933, 8,104,515, 8,220,487, and 8,550,119.   Fluidigm IFCs may not be used with any non-Fluidigm system, and Fluidigm systems (including the Biomark HD, C1, Callisto, EP1, Juno, and Polaris Systems) may not be used with any device other than Fluidigm IFCs. Fluidigm IFCs are single use only and may not be reused unless otherwise specifically authorized in writing by Fluidigm. No other licenses are granted, expressed or implied.

Access Array™ IFC

Fluidigm Product Patent Notice

The Fluidigm Access Array IFC, methods for controlling the Access Array IFC, and/or the manufacture of the Access Array IFC may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 6,408,878, 6,645,432, 6,719,868, 6,793,753, 6,929,030, 7,040,338, 7,323,143, 7,479,186, 7,601,270, 7,867,763, 8,002,933, 8,104,515, 8,105,824, 8,220,487, 8,550,119 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

Dynamic Array™ IFCs

Fluidigm Product Patent Notice

Fluidigm Dynamic Array IFCs (including the Flex Six IFC, 48.48 Dynamic Array IFCs, 96.96 Dynamic Array IFCs, and 192.24 Dynamic Array IFC), methods for reading and controlling Dynamic Array IFCs, and/or the manufacture of Dynamic Array IFCs may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,479,186, 8,007,746, 6,408,878, 6,645,432, 6,719,868, 6,793,753, 6,929,030, 7,040,338, 7,323,143, 7,476,363, 7,601,270, 7,867,454, 7,867,763, 8,002,933, 8,104,515, 8,105,824, 8,157,434, 8,220,487, 8,420,017, 8,475,743, 8,550,119, 8,591,834, 8,616,227 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

Digital Array™ IFCs

Fluidigm Product Patent Notice

Fluidigm Digital Array IFCs (including the 12.765 Digital Array IFC, 48.770 Digital Array IFC, and qdPCR 37K IFC), methods for reading and controlling Digital Array IFCs, and/or the manufacture of Digital Array IFCs may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 6,408,878, 6,645,432, 6,719,868, 6,793,753, 6,929,030, 7,040,338, 7,323,143, 7,479,186, 7,601,270, 7,604,965, 7,666,361, 7,691,333, 7,749,737, 7,837,946, 7,867,763, 8,002,933, 8,104,515, 8,105,824, 8,163,492, 8,220,487, 8,247,178, 8,550,119 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

C1™ IFCs

Fluidigm Product Patent Notice

Fluidigm C1 IFCs, methods for reading and controlling C1 IFCs, and/or the manufacture of C1 IFCs may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 6,408,878, 6,645,432, 6,719,868, 6,767,706, 6,793,753, 6,929,030, 7,040,338, 7,323,143, 7,479,186, 7,601,270, 7,867,763, 8,002,933, 8,104,515, 8,105,824, 8,129,176, 8,220,487, 8,257,666, 8,455,258, 8,550,119, 8,673,645, 8,871,446 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

Callisto™ IFC

Fluidigm Product Patent Notice

The Fluidigm Callisto IFC, methods for reading and controlling the Callisto IFC, and/or the manufacture of the Callisto IFC may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 6,408,878, 6,645,432, 6,719,868, 6,793,753, 6,929,030, 7,040,338, 7,323,143, 7,479,186, 7,601,270, 7,867,763, 8,002,933, 8,104,515, 8,105,824, 8,220,487, 8,550,119, 8,673,645, 8,871,446 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

Juno™ IFC

Fluidigm Product Patent Notice

The Fluidigm Juno IFC (integrated fluidic circuits/microfluidic chips with or without a carrier), methods for reading and controlling the Juno IFC, and/or the manufacture of the Juno IFCs may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 6,408,878, 6,645,432, 6,719,868, 6,793,753, 6,929,030, 7,040,338, 7,323,143, 7,479,186, 7,601,270, 7,604,965, 7,666,361, 7,691,333, 7,749,737, 7,867,763, 8,002,933, 8,104,515, 8,105,824, 8,163,492, 8,220,487, 8,247,178, 8,550,119 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

Polaris™ IFC

Fluidigm Product Patent Notice

The Fluidigm Polaris IFC, methods for reading and controlling the Polaris IFC, and/or the manufacture of the Polaris IFC may be covered by one or more of the following patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 6,408,878, 6,645,432, 6,719,868, 6,793,753, 6,802,342, 6,899,137, 6,929,030, 7,040,338, 7,323,143, 7,479,186, 7,601,270, 7,867,763, 8,002,933, 8,104,515, 8,105,824, 8,220,487, 8,455,258, 8,550,119, 8,673,645 and additional issued and pending patents in the U.S. and other countries.
For Research Use Only. Not for use in diagnostic procedures.

NOTICE TO PURCHASER: Limited Use License to Perform Digital PCR with Fluidigm IFCs.
The purchase of a Digital Array IFC from Fluidigm Corporation and/or its affiliates (collectively Fluidigm) conveys to the purchaser the limited, non-transferable right to the purchaser to use the purchased amount of this product in all fields other than in the Sequencing Field, the Mass Spectrometry Field and the Prenatal Field to perform digital PCR methods under license from Thermo Fisher Scientific. No right to resell this product and no other rights (such as real-time PCR methods, apparatus, reagents or software to perform digital PCR methods) are conveyed by Thermo Fisher Scientific expressly, by implication, or by estoppel. For information on obtaining additional rights, please contact outlicensing@lifetech.com.

NOTICE TO PURCHASER: Limited Use License to Perform Pre-Amplification with Fluidigm IFCs.
The purchase of an IFC from Fluidigm Corporation and/or its affiliates (collectively Fluidigm) conveys to the purchaser the limited, non-transferable right to perform pre-amplification methods under license from Thermo Fisher Scientific for use with the purchased amount of this product and Fluidigm instruments. No right to resell this product and no other rights (such as real-time PCR methods, apparatus, reagents or software to perform digital PCR methods) are conveyed by Thermo Fisher Scientific expressly, by implication, or by estoppel. For information on obtaining additional rights, please contact outlicensing@lifetech.com.

Access Array Target Specific Primers and Reagents Patent Notice June 11, 2014

Access Array Target Specific Primers and Reagents

Fluidigm Product Patent Notice

This product and its use with the Access Array System may be covered U.S. Patent 8,691,509, owned by Fluidigm Corporation, and additional foreign patents and pending patent applications.

For Research Use Only.  Not for use in diagnostic procedures.

Fluidigm Reverse Transcription Master Mix Patent Notice June 11, 2014

Fluidigm Reverse Transcription Master Mix

Fluidigm Product Patent Notice

The use of Fluidigm Reverse Transcription Master Mix together with Fluidigm products including IFCs (integrated fluidic circuits/microfluidic chips with or without a carrier) such as C1 Single-Cell Auto Prep Array IFCs, Access Array IFCs, Dynamic Array IFCs and Digital Array IFCs, the IFC controller, FC1 Cycler and the Fluidigm system (C1 Single-Cell Auto Prep System, Biomark HD System, EP1 System, readers, thermal cycler, etc.) and methods for reading and controlling the C1 Single-Cell Auto Prep Array IFCs, Access Array IFCs, Dynamic Array IFCs and Digital Array IFCs and/or their use and manufacture may be covered by one or more of the following patents owned by Fluidigm Corporation and/or sold under license from California Institute of Technology and other entities: : U.S. Patent Nos. 6,408,878, 6,645,432, 6,719,868, 6,793,753, 6,929,030, 7,195,670, 7,216,671, 7,307,802, 7,323,143, 7,476,363, 7,479,186, 7,494,555, 7,588,672, 7,601,270, 7,604,965, 7,666,361, 7,691,333, 7,704,735, 7,749,737, 7,766,055, 7,815,868, 7,837,946, 7,867,454, 7,867,763, 7,906,072, 8,048,378, 8,104,497, 8,104,515, 8,105,553, 8,105,824, 8,129,176, 8,157,434, 8,163,492, 8,273,574, 8,257,666, 8,389,960, 8,512,640, 8,616,227, 8,721,968; and additional issued and pending patents in the U.S. and other countries.

Fluidigm, the Fluidigm logo, Access Array, Biomark, C1, Dynamic Array, Digital Array, EP1, and FC1, are trademarks or registered trademarks of Fluidigm Corporation in the U.S. and/or other countries.

© Fluidigm Corporation. All rights reserved.

For Research Use Only. Not for use in diagnostic procedures.

Maxpar and Cell-ID Reagents Patent Notice and Limited License January 1, 2018

Maxpar and Cell-ID Reagents Patent Notice and Limited License January 1, 2018 Maxpar® Metal Conjugated Antibodies, Maxpar® Panel Kits, Maxpar® Metal Labeling Kits, and Cell-ID™ Cell Labeling Reagents (Collectively Maxpar and Cell-ID reagents)

Fluidigm Product Patent Notice

The Maxpar and Cell-ID reagents and their use with the CyTOF®, CyTOF® 2, Helios™, and Hyperion™ Imaging Systems may be covered by one or more of the following U.S. Patents owned or licensed by Fluidigm Corporation and/or its affiliates: 7,135,296, 7,479,630, 7,700,295, 7,767,407, 8,003,312, 8,101,368, 8,236,511, 8,354,242, 9,012239, 9,176,137, 9,296,838, 10,072,104 and additional foreign patents and pending patent applications. Fluidigm, the Fluidigm logo, Cell-ID, CyTOF, Helios, Hyperion, and Maxpar are trademarks and/or registered trademarks of Fluidigm Corporation in the U.S. and/or other countries.

Fluidigm, the Fluidigm logo, Cell-ID, CyTOF, Helios, Hyperion, and Maxpar are trademarks and/or registered trademarks of Fluidigm Corporation in the U.S. and/or other countries

For Research Use Only. Not for use in diagnostic procedures.

Note to Purchaser: Limited License

Use of the Maxpar and Cell-ID reagents is covered by one or more of the following US patents owned or licensed by Fluidigm Corporation and/or its affiliates (collectively Fluidigm): U.S. Patent Nos. 7,135,296, 7,479,630, 7,700,295, 7,767,407, 8,003,312, 8,101,368, 8,236,511, 8,354,242, 9,012239, 9,176,137, 9,296,838, 10,072,104 and additional foreign patents and pending patent applications. The purchase of Maxpar and Cell-ID reagents conveys from Fluidigm to the purchaser a limited, non-transferable right to use the reagents only with Fluidigm instruments and systems (CyTOF®, CyTOF® 2, Helios™, and Hyperion™ Imaging Systems). For information on obtaining additional usage rights, please contact Fluidigm at www.fluidigm.com/support.

PreAmp Master Mix Patent Label and Limited License June 11, 2014

Fluidigm PreAmp Master Mix

Fluidigm Product Patent Notice and Limited License

The use of Fluidigm PreAmp Master Mix together with Fluidigm products including IFCs (integrated fluidic circuits/microfluidic chips with or without a carrier) such as C1 Single-Cell Auto Prep Array IFCs, Access Array IFCs, Dynamic Array IFCs and Digital Array IFCs, the IFC controller, FC1 Cycler and the Fluidigm system (Biomark HD System, EP1 System, readers, thermal cycler, etc.) and methods for reading and controlling the C1 Single-Cell Auto Prep Array IFCs, Access Array IFCs, Dynamic Array IFCs and Digital Array IFCs and/or their use and manufacture may be covered by one or more of the following patents owned by Fluidigm Corporation and/or sold under license from California Institute of Technology and other entities: U.S. Patent Nos. 6,408,878, 6,645,432, 6,719,868, 6,793,753, 6,929,030, 7,195,670, 7,216,671, 7,307,802, 7,323,143, 7,476,363, 7,479,186, 7,494,555, 7,588,672, 7,601,270, 7,604,965, 7,666,361, 7,691,333, 7,704,735, 7,749,737, 7,766,055, 7,815,868, 7,837,946, 7,867,454, 7,867,763, 7,906,072, 8,048,378, 8,104,497, 8,104,515, 8,105,553, 8,105,824, 8,129,176, 8,157,434, 8,163,492, 8,273,574, 8,257,666, 8,389,960, 8,512,640, 8,616,227, 8,721,968; and additional issued and pending patents in the U.S. and other countries.

Fluidigm, the Fluidigm logo, Access Array, Biomark, C1, Dynamic Array, Digital Array, EP1, and FC1, are trademarks or registered trademarks of Fluidigm Corporation in the U.S. and/or other countries. © Fluidigm Corporation. All rights reserved.

For Research Use Only. Not for use in diagnostic procedures.

NOTICE TO PURCHASER: Limited Use License to Perform Preamplification with Fluidigm IFCs. The purchase of a C1 Single-Cell Auto Prep Array IFC , Digital Array IFC, or Dynamic Array IFC from Fluidigm Corporation conveys to the purchaser the limited, non-transferable right to perform preamplification methods under license from Life Technologies Corporation for use with the purchased amount of this product and Fluidigm instruments. No right to resell this product and no other rights (such as real-time PCR methods, apparatus, reagents or software to perform digital PCR methods) are conveyed by Life Technologies Corporation expressly, by implication, or by estoppel. For information on obtaining additional rights, please contact outlicensing@lifetech.com or Out Licensing, Life Technologies, 5791 Van Allen Way, Carlsbad, California 92008. For information about the scope of the above-identified Fields, please contact labellicenseinformation@fluidigm.com.