The Revolution at Hand
The world's first automated solution for single-cell genomics research, the C1™ Single-Cell Auto Prep system employs our innovative microfluidic technology to rapidly and reliably isolate, process and prepare individual cells for genome and transcriptome analysis. With just one instrument, you can isolate cells, stain them and prepare template for sequencing or qPCR. Though we’re sure you'll do much more than that.
Discover differences in heterogeneous populations with single-cell accuracy
Easily isolate and process individual cells with a streamlined workflow and intuitive interface
Minimize hands-on time with an automated cell-to-data workflow
Get DNA and mRNA seq, targeted gene expression and miRNA template with one platform
The innovative C1 system carefully isolates single cells into individual reaction chambers in Fluidigm's exclusive integrated fluidic circuit (IFC). The optically clear IFC lets you automatically stain captured cells and examine them by microscopy for viability, surface markers or reporter genes. After staining, cells are automatically lysed and template is quickly prepared for qPCR or sequencing analysis—all in as little as four hours.
Prime the C1 IFC in preparation for sample transfer.
Insert the IFC into C1 to automatically isolate up to 96 individual cells to separate reaction chambers.
Label each cell and microscopically image the IFC to confirm cell count and viability.
Reinsert the IFC into C1 to lyse each cell for amplification.
Magnify each cell’s genomic content for sequencing or qPCR detection.
Collect product from the C1 outlet.
IFCs, Assays and Reagents
Achieve highly reliable and reproducible data from individual cells with our latest microfluidic IFCs, designed to capture cells from 5 to 25 µm. Created specifically for C1™ systems.
C1 Reagent Kit
Automate your single-cell research with our ready-to-use reagent solutions for DNA sequencing, mRNA sequencing and targeted gene expression.
Singular Analysis Toolset
An innovative, open-source solution for analyzing and visualizing data, the Singular™ Analysis Toolset offers powerful methods for identifying gene expression and mutation patterns at the single-cell level. Designed for use with Biomark™ and C1™ systems.
Singular Practice Sets v3.5.2
C1 system software v2.0
The latest system software upgrade for C1 supports IFC for Open App in addition to DNA sequencing, mRNA sequencing, targeted gene expression and miRNA analysis.
|Clearance||6 in (15 cm) from the rear|
|Temperature||59–82 °F (15–28 °C) stable|
|Altitude||<8,202 ft. (2,500 m)|
Refer to the C1 System Site Requirements (PN 100-5201) for more information on operating requirements.
|Height||30 in (76 cm)|
|Width||28 in (71 cm)|
|Depth||39 in (99cm)|
|Weight||159 lb (72 kg)|
|Height||19 in (48 cm)|
|Width||16 in (41 cm)|
|Weight||103 lb (46.7 kg)|
|Thermal control||Peltier-based, 4–99 °C|
|Max heating rate||>4 °C/sec|
|Max cooling rate:||>3 °C/sec|
|IFC compatibility||C1 IFCs|
|Current||9 A (max)|
|Main supply fluctuation||Not to exceed ±10% of the nominal supply voltage|