Successful targeted sequencing depends on quality library preparation, and successful prep depends on the Access Array™ system. Since its launch in 2009, Access Array has been an indispensible support tool for high-throughput sequencing, targeted enrichment and library preparation for some of the world’s leading laboratories.
Browse our catalog of related publications to learn how Access Array enables researchers around the globe to do more with much less when it comes to library prep.
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Overview
Number of papers per research area as of February, 2021Number of cumulative papers as of February, 2021 -
Recent
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NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis
Peri, S., Izumchenko, E., Schubert, A.D. et al. Nature Communications (2017): 1,772 -
Regulation of gene expression and RNA editing in Drosophila adapting to divergent microclimates
Yablonovitch, A.L., Fu, J., Li, K. et al. Nature Communications (2017): 1,570 -
Characterization of a thermo-inducible chlorophyll-deficient mutant in barley
Wang, R., Yang, F., Zhang, X.Q. et al. Frontiers in Plant Science (2017): 1,936 -
Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia
Wen, W.X., Allen, J., Lai, K.N. et al. Journal of Medical Genetics (2018): 97–103 -
A new perspective on polyploid Fragaria (strawberry) genome composition based on large-scale, multi-locus phylogenetic analysis
Yang, Y., Davis, T.M. Genome Biology and Evolution (2017): 3,433–48
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NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis
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Research Areas
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Biomarker Screening
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Mutation detection in cholestatic patients using microarray resequencing of ATP8B1 and ABCB11
McKay, K.E., Bruce, C.K., Hartley, J.L. et al. F1000 Research (2013): 32 -
Methylomic analysis of salivary DNA in childhood ADHD identifies altered DNA methylation in VIPR2
Wilmot, B., Fry, R., Smeester, L. et al. Journal of Child Psychology and Psychiatry (2016): 152–60 -
Rapid detection of monogenic causes of childhood-onset steroid-resistant nephrotic syndrome
Lovric, S., Fang, H., Vega-Warner, V. et al. Clinical Journal of the American Society of Nephrology (2014): 1,109–16 -
ABCA4 gene screening by next-generation sequencing in a British cohort
Fujinami, K., Zernant, J., Chana, R.K. et al. Investigative Opthalmology and Visual Science (2013): 6,662–74 -
Efficient detection of novel nuclear markers for Brassicaceae by transcriptome sequencing
Stockenhuber, R., Zoller, S., Shimizu-Inatsugi, R. et al. PLoS One (2015): e0128181 -
Genetic analysis of the cardiac methylome at single nucleotide resolution in a model of human cardiovascular disease
Johnson, M.D., Mueller, M., Adamowicz-Brice, M. et al. PLoS Genetics (2014): e1004813 -
A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome
Sadowski, C.E., Lovric, S., Ashraf, S. et al. Journal of the American Society of Nephrology (2015): 1,279–89 -
CSN1 somatic mutations in penile squamous cell carcinoma
Feber, A., Worth, D.C., Chakravarthy, A. et al. Cancer Research (2016): 4,720–7 -
Prevalence of monogenic causes in pediatric patients with nephrolithiasis or nephrocalcinosis
Braun, D.A., Lawson, J.A., Gee, H.Y. et al. Clinical Journal of the American Society of Nephrology (2016): 664–72 -
A highly sensitive and quantitative test platform for detection of NSCLC EGFR mutations in urine and plasma
Reckamp, K.L., Melnikova, V.O., Karlovich, C. et al. Journal of Thoracic Oncology (2016): 1,690–700 -
Targeted re-sequencing approach of candidate genes implicates rare potentially functional variants in Tourette Syndrome etiology
Alexander, J., Potamianou, H., Xing, J. et al. Frontiers in Neuroscience (2016): 428 -
Characterization of a thermo-inducible chlorophyll-deficient mutant in barley
Wang, R., Yang, F., Zhang, X.Q. et al. Frontiers in Plant Science (2017): 1,936 -
Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation
Paliwal, A., Temkin, A.M., Kerkel, K. et al. PLOS Genetics (2013): e1003622 -
Physiological effects of stress related to helicopter travel in Federal Emergency Management Agency search-and-rescue canines
Perry, E., Gulson, N., Liu Cross, T.W. et al. Journal of Nutritional Science (2017): e28 -
Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxia
Roche, O., Deguiz, M.L., Tiana, M. et al. Nucleic Acids Research (2016): 9,315–30 -
Mutational analysis clopidogrel resistance and platelet function in patients scheduled for coronary artery bypass grafting
Correll, M., Johnson, C.K., Ferrari, G. et al. Genomics (2013): 313–7 -
CTNS mutations in publicly-available human cystinosis cell lines
Zykovich, A., Kinkade, R., Royal, G., Zankel, T. Molecular Genetics and Metabolism Reports (2015): 63–6 -
A lung cancer risk classifier comprising genome maintenance genes measured in normal bronchial epithelial cells
Yeo, J., Crawford, E.L., Zhang, X. et al. BMC Cancer (2017): 301 -
Species-specific control of external superoxide levels by the coral holobiont during a natural bleaching event
Diaz, J.M., Hansel, C.M., Apprill, A. et al. Nature Communications (2016): 13,801 -
Targeted sequencing identifies patients with preclinical MDS at high risk of disease progression
Cargo, C.A., Rowbotham, N., Evans, P.A. et al. Blood (2015): 2,362–5 -
Deep sequencing reveals spatially distributed distinct hotspot mutations in DICER1-related multinodular goiter
de Kock, L., Bah, I., Revil, T. et al. Journal of Clinical Endocrinology and Metabolism (2016): 3,637–45 -
Implementation of digital technology solutions for a lung health trial in rural Malawi
Chisunkha, B., Banda, H., Thomson, R. et al. European Respiratory Journal (2016): 1,876–9 -
Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants
Duan, J., Sanders, A.R., Moy, W. et al. Human Molecular Genetics (2015): 4,674–85 -
A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene
Ding, Y., Long, P.A., Bos, J.M., et al. JCI Insight (2016): e88797 -
Prevalence of familial hypercholesterolemia among young north Karelian patients with coronary heart disease: a study based on diagnosis by polymerase chain reaction
Koivisto, U.M., Hämäläinen, L., Taskinen, M.R. et al. Journal of Lipid Research (1993): 269–77 -
Fourteen monogenic genes account for 15% of nephrolithiasis/nephrocalcinosis
Halbritter, J., Baum, M., Hynes, A.M. et al. Journal of the American Society of Nephrology (2015): 543–51 -
Mutations in nuclear pore genes NUP93, NUP205, and XPO5 cause steroid resistant nephrotic syndrome
Braun, D.A., Sadowski, C.E., Kohl, S. et al. Nature Genetics (2016): 457–65 -
Visualizing the origins of selfish de novo mutations in individual seminiferous tubules of human testes
Maher, G.J., McGowan, S.J., Giannoulatou, E. et al. Proceedings of the National Academy of Sciences of the United States of America (2016): 2,454–9 -
MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance
Kwok, B., Hall, J.M., Witte, J.S. et al. Blood (2015): 2,355–61 -
Whole-exome sequencing in individuals with multiple cardiovascular risk factors and normal coronary arteries
Abramowitz, Y., Roth, A., Keren, G., et al. Coronary Artery Disease (2016): 257–66
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Mutation detection in cholestatic patients using microarray resequencing of ATP8B1 and ABCB11
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Carrier Screening
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IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype
Perrault, I., Halbritter, J., Porath, J.D. et al. Journal of Medical Genetics (2015): 657–65 -
Expanding preconception carrier screening for the Jewish population using high throughput microfluidics technology and next generation sequencing
Gal, M., Khermesh, K., Barak, M. et al. BMC Medical Genomics (2016): 24
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IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype
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Data Analysis Methods
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CYBERTRACK2.0: zero-inflated model-based cell clustering and population tracking method for longitudinal mass cytometry data
Minoura, K., Abe, K., Maeda, Y. Bioinformatics (2020): DOI: 10.1093/bioinformatics/btaa873
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CYBERTRACK2.0: zero-inflated model-based cell clustering and population tracking method for longitudinal mass cytometry data
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Fingerprinting/Sample ID
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Robust detection of individual forensic profiles in DNA mixtures
Isaacson, J., Schwoebel, E., Shcherbina, A. et al. Forensic Science International: Genetics (2014): 31–7
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Robust detection of individual forensic profiles in DNA mixtures
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HLA Typing
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Very high resolution single pass HLA genotyping using amplicon sequencing on the 454 next generation DNA sequencers: Comparison with Sanger sequencing
Yamamoto, F., Höglund, B., Fernandez-Vina, M. et al. Human Immunology (2015): 910–16 -
Survey of major histocompatibility complex class II diversity in pig-tailed macaques
Karl, J.A., Heimbruch, K.E., Vriezen, C.E. et al. Immunogenetics (2014): 613–23 -
Cost-efficient high-throughput HLA typing by MiSeq amplicon sequencing
Lange, V., Böhme, I., Hofmann, J. et al. BMC Genomics (2014): 63 -
High throughput HLA genotyping using 454 sequencing and the Fluidigm Access Array™ system for simplified amplicon library preparation
Moonsamy, P.V., Williams, T., Bonella, P. et al. Tissue Antigens (2013): 141–9 -
Prediction of spurious HLA class II typing results using probabilistic classification
Schöfl, G., Schmidt, A.H., Lange, V. Human Immunology (2016): 264–72
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Very high resolution single pass HLA genotyping using amplicon sequencing on the 454 next generation DNA sequencers: Comparison with Sanger sequencing
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Immunology
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One million samples typed by NGS: lessons learned
Lange, V., Boehme, I., Paul, P. et al. Human Immunology (2015): 210 -
Burn injury alters the intestinal microbiome and increases gut permeability and bacterial translocation
Earley, Z.M., Akhtar, S., Green, S.J. et al. PLoS One (2015): e0129996 -
Discovery of invariant T cells by next generation sequencing of the human T cell receptor α chain repertoire
van Schaik, B., Klarenbeek, P., Doorenspleet, M. et al. Journal of Immunology (2014): 5,338–44 -
Restricting nonclassical MHC genes coevolve with TRAV genes used by innate-like T cells in mammals
Boudinot, P., Mondot, S., Jouneau, L. et al. Proceedings of the National Academy of Sciences of the United States of America (2016): e2983–92
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One million samples typed by NGS: lessons learned
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Inherited Disease
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High-throughput mutation analysis in patients with a nephronophthisis-associated ciliopathy applying multiplexed barcoded array-based PCR amplification and next-generation sequencing
Halbritter, J., Diaz, K., Chaki, M. et al. Journal of Medical Genetics (2012): 756–67 -
Towards clinical molecular diagnosis of inherited cardiac conditions: A comparison of bench-top genome DNA sequencers
Li, X., Buckton, A.J., Wilkinson, S.L. et al. PLoS One (2013): e67744 -
Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study
Norsworthy, P.J., Vandrovcova, J., Thomas, E.R.A. et al. BMC Medical Genetics (2014): 70 -
Exome sequencing of 75 individuals from multiply affected coeliac families and large scale resequencing follow up
Mistry, V., Bockett, N.A., Levine, A.P. et al. PLoS One (2015): e0116845 -
IGSF10 mutations dysregulate gonadotropin‐releasing hormone neuronal migration resulting in delayed puberty
Howard, S.R., Guasti, L., Ruiz-Babot, G. et al. EMBO Molecular Medicine (2016): 626–42 -
Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish
Shamay-Ramot, A., Khermesh, K., Porath, H.T. et al. PLoS Genetics (2015): e1005702 -
Mutations in RASA1 and GDF2 identified in patients with clinical features of hereditary hemorrhagic telangiectasia
Hernandez, F., Huether, R., Carter, L. et al. Human Genome Variation (2015): 15,040 -
Next generation diagnostics in inherited arrhythmia syndromes: A comparison of two approaches
Ware, J.S., John, S., Roberts, A.M. et al. Journal of Cardiovascular Translational Research (2013): 94–103 -
Novel form of X-linked nonsyndromic hearing loss with cochlear malformation caused by a mutation in the type IV collagen gene COL4A6
Rost, S., Bach, E., Neuner, C. et al. European Journal of Human Genetics (2014): 208–15 -
Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome)
Glover, M., Ware, J.S., Henry, A. et al. Clinical Science (2014): 721–6 -
Mutations in 12 known dominant disease-causing genes clarify many congenital anomalies of the kidney and urinary tract
Hwang, D.Y., Dworschak, G.C., Kohl, S. et al. Kidney International (2014): 1,429–33 -
Haploinsufficiency of insulin gene enhancer protein 1 (ISL1) is associated with d-transposition of the great arteries
Osoegawa, K., Schultz, K., Yun, K. et al. Molecular Genetics & Genomic Medicine (2014): 341–51 -
Mild recessive mutations in six Fraser syndrome–related genes cause isolated congenital anomalies of the kidney and urinary tract
Kohl, S., Hwang, D.Y., Dworschak, G.C. et al. Journal of the American Society of Nephrology (2014): 1,917–22 -
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
Kato, N., Loh, M., Takeuchi, F. et al. Nature Genetics (2015): 1,282–93 -
A recurrent mutation in CACNA1G alters Cav3.1 T-type calcium-channel conduction and causes autosomal-dominant cerebellar ataxia
Coutelier, M., Blesneac, J., Monteil, A. et al. American Journal of Human Genetics (2015): 726–37 -
AP5Z1/SPG48 frequency in autosomal recessive and sporadic spastic paraplegia
Schlipf, N.A., Schüle, R., Klimpe, S. et al. Molecular Genetics and Genomic Medicine (2014): 379–82 -
Diagnostic approach for FSHD revisited: SMCHD1 mutations cause FSHD2 and act as modifiers of disease severity in FSHD1
Larsen, M., Rost, S., Hajj, N.E. et al. European Journal of Human Genetics (2015): 808–16 -
DCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signaling
Schueler, M., Braun, D.A., Chandrasekar, G. et al. The American Journal of Human Genetics (2015): 81–92 -
Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract
Hwang, D.Y., Kohl, S., Fan, X., et al. Human Genetics (2015): 905–16 -
AmpliVar: Mutation detection in high-throughput sequence from amplicon-based libraries
Hsu, A.L., Kondrashova, O., Lunke, S. et al. Human Mutation (2015): 411–8 -
Microfluidic amplification as a tool for massive parallel sequencing of familial hypercholesterolemia genes
Hollants, S., Redeker, E.J., Matthijs, G. American Association for Clinical Chemistry (2012): 717–24 -
Differential methylation is associated with non-syndromic cleft lip and palate and contributes to penetrance effects
Alvizi, L., Ke, X., Brito, L.A. et al. Scientific Reports (2017): 2,441 -
Prevalence of DNA-confirmed familial hypercholesterolaemia in young patients with myocardial infarction
Wald, D.S., Bangash, F.A., Bestwick, J.P. European Journal of Internal Medicine (2015): 127–30 -
Large-scale targeted sequencing comparison highlights extreme genetic heterogeneity in nephronophthisis-related ciliopathies
Schueler, M., Halbritter, J., Phelps, I.G. et al. Journal of Medical Genetics (2016): 208–14 -
High-sensitivity sequencing reveals multi-organ somatic mosaicism causing DICER1 syndrome
de Kock, L., Wang, Y.C., Revil, T. et al. Journal of Medical Genetics (2016): 43–52 -
Genetic epidemiology of motor neuron disease-associated variants in the Scottish population
Black, H.A., Leighton, D.J., Cleary, E.M. et al. Neurobiology of Aging (2017): 51 -
Recessive nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum is caused by homozygous protein-truncating mutations of WDR73
Jinks, R.N., Puffenberger, E.G., Baple, E., et al. Brain (2015): 2,173–90 -
Identification of 99 novel mutations in a worldwide cohort of 1,056 patients with a nephronophthisis-related ciliopathy
Halbritter, J., Porath, J., Diaz, K. et al. Human Genetics (2013): 865–84 -
Negligible impact of rare autoimmune locus coding-region variants on missing heritability
Hunt, K.A., Mistry, V., Bockett, N.A. et al. Nature (2013): 232–5 -
Genetic and clinical characterization of Pakistani families with Bardet-Biedl syndrome extends the genetic and phenotypic spectrum
Maria, M., Lamers, I.J.C., Schmidts, M. et al. Scientific Reports (2016): 34,764 -
Amplicon-based high-throughput pooled sequencing identifies mutations in CYP7B1 and SPG7 in sporadic spastic paraplegia patients
Schlipf, N.A., Schüle, R., Klimpe, S. et al. Clinical Genetics (2011): 148–60 -
Targeted PCR-based enrichment and next generation sequencing for diagnostic testing of congenital disorders of glycosylation (CDG)
Jones, M., Bhide, S., Chin, E. et al. Genetics in Medicine (2011): 921–32 -
Activating mutations affecting the Dbl homology domain of SOS2 cause Noonan syndrome
Cordeddu, V., Yin, J.C., Gunnarsson, C., Virtanen, C., Drunat, S., Lepri, F., De Luca, A., Rossi, C., Ciolfi, A., Pugh, T.J., Bruselles, A., Priest, J.R., Pennacchio, L.A., Lu, Z., Danesh, A., Quevedo, R., Hamid, A., Martinelli, S., Pantaleoni, F., Gnazzo, M., Daniele, P., Lissewski, C., Bocchinfuso, G., Stella, L., Odent, S., Philip, N., Faivre, L., Vlckova, M., Seemanova, E., Digilio, C., Zenker, M., Zampino, G., Verloes, A., Dallapiccola, B., Roberts, A.E., Cavé, H., Gelb, B.D., Neel, B.G., Tartaglia, M. Human Mutation (2015): 1080–7 -
Heterozygous HTRA1 mutations are associated with autosomal dominant cerebral small vessel disease
Verdura, E., Hervé, D., Scharrer, E., Amador, M.D., Guyant-Maréchal, L., Philippi, A., Corlobé, A., Bergametti, F., Gazal, S., Prieto-Morin, C., Beaufort, N., Le Bail, B., Viakhireva, I., Dichgans, M., Chabriat, H., Haffner, C., Tournier-Lasserve, E. Brain - A Journal of Neurology (2015): 2347–58 -
Alteration of ornithine metabolism leads to dominant and recessive hereditary spastic paraplegia
Coutelier, M., Goizet, C., Durr, A., Habarou, F., Morais, S., Dionne-Laporte, A., Tao, F., Konop, J., Stoll, M., Charles, P., Jacoupy, M., Matusiak, R., Alonso, I., Tallaksen, C., Mairey, M., Kennerson, M., Gaussen, M., Schule, R., Janin, M., Morice-Picard, F., Durand, C.M., Depienne, C., Calvas, P., Coutinho, P., Saudubray, J.M., Rouleau, G., Brice, A., Nicholson, G., Darios, F., Loureiro, J.L., Zuchner, S., Ottolenghi, C., Mochel, F., Stevanin, G. Brain - A Journal of Neurology (2015): 2191–205 -
Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A
Bronicki, L.M., Redin, C., Drunat, S., Piton, A., Lyons, M., Passemard, S., Baumann, C., Faivre, L., Thevenon, J., Rivière, J.B., Isidor, B., Gan, G., Francannet, C., Willems, M., Gunel, M., Jones, J.R., Gleeson, J.G., Mandel, J.L., Stevenson, R.E., Friez, M.J., Aylsworth, A.S. European Journal of Human Genetics (2015): 1482–7
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High-throughput mutation analysis in patients with a nephronophthisis-associated ciliopathy applying multiplexed barcoded array-based PCR amplification and next-generation sequencing
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Liquid Biopsy
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Targeted error-suppressed quantification of circulating tumor DNA using semi-degenerate barcoded adapters and biotinylated baits
Alcaide, M., Yu, S., Davidson, J. et al. Scientific Reports (2017): doi: 10.1038/s41598-017-10269-2 -
Circulating tumor DNA and circulating tumor cells in metastatic triple negative breast cancer patients
Madic, J., Kiialainen, A., Bidard, F.C. et al. International Journal of Cancer (2014): 2,158–65 -
Circulating tumour DNA reflects treatment response and clonal evolution in chronic lymphocytic leukaemia
Yeh, P., Hunter, T., Sinha, D. et al. Nature Communications (2017): 14,756 -
PPM1D Mutations in Circulating White Blood Cells and the Risk for Ovarian Cancer
Akbari, M.R., Lepage, P., Rosen, B. et al. Journal of the National Cancer Institute (2013): djt323 -
Circulating Cell Free Tumor DNA Detection as a Routine Tool for Lung Cancer Patient Management
Vendrell, J.A., Mau-Them, F.T., Béganton, B. et al. International Journal of Molecular Sciences (2017): 264
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Targeted error-suppressed quantification of circulating tumor DNA using semi-degenerate barcoded adapters and biotinylated baits
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Marker Assisted Breeding
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Next generation haplotyping to decipher nuclear genomic interspecific admixture in Citrus species: analysis of chromosome 2
Curk, F., Ancillo, G., Garcia-Lor, A. et al. BMC Genetics (2014): 152 -
Fine Mapping of the Barley Chromosome 6H Net Form Net Blotch Susceptibility Locus
Richards, J., Chao, S., Friesen, T., Brueggeman, R. G3 (2016): 1,809–18 -
Clusters of Antibiotic Resistance Genes Enriched Together Stay Together in Swine Agriculture
Johnson, T.A., Stedtfeld, R.D., Wang, Q., et al. mBio (2016): e02214–5 -
Multilocus Haplotyping by Parallel Sequencing to Decipher the Interspecific Mosaic Genome Structure of Cultivated Citrus
Curk, F., Ancillo, G., Garcia-Lor, A. et al. International Society for Horticultural Science (2015): DOI: 10.17660/ActaHortic.2015.1065.11 -
Whole‐genome sequencing reveals small genomic regions of introgression in an introduced crater lake population of threespine stickleback
Yoshida, K., Miyagi, R., Mori, S., Takahashi, A., Makino, T., Toyoda, A., Fujiyama, A., Kitano, J. Ecology and Evolution (2016): 2,190–204 -
Nuclear Species-Diagnostic SNP Markers Mined from 454 Amplicon Sequencing Reveal Admixture Genomic Structure of Modern Citrus Varieties
Curk, F., Ancillo, G., Ollitraut, F., Perrier, X., Jacquemoud-Collet, J.P., Garcia-Lor, A., Navarro, L., Ollitraut, P. PLoS One (2015): e0125628
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Next generation haplotyping to decipher nuclear genomic interspecific admixture in Citrus species: analysis of chromosome 2
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Method Development
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Primers for Castilleja and their utility across Orobanchaceae: II. Single-copy nuclear loci
Latvis, M., Jacobs, S.J., Mortimer, S.M.E. et al. Applications in Plant Sciences (2017): doi: 10.3732/apps.1700038 -
Robust high-performance nanoliter-volume single-cell multiple displacement amplification on planar substrates
Leung, K., Klaus, A., Lin, B.K. et al. Proceedings of the National Academy of Sciences of the United States of America (2016): 8,484–9 -
Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial Cells
Gong, H., Liu, M., Klomp, J. et al. Scientific Reports (2017): 42,127 -
MPD: multiplex primer design for next-generation targeted sequencing
Wingo, T.S., Kotlar, A., Cutler, D.J. BMC Bioinformatics (2017): 14 -
Home-Made Cost Effective Preservation Buffer Is a Better Alternative to Commercial Preservation Methods for Microbiome Research
Menke, S., Gillingham, M.A.F., Wilhelm, K. et al. Frontiers in Microbiology (2017): 102 -
Targeted enrichment strategies for next-generation plant biology
Cronn, R., Knaus, B.J., Liston, A., et al. American Journal of Botany (2012): 291–311 -
tarSVM: Improving the accuracy of variant calls derived from microfluidic PCR-based targeted next generation sequencing using a support vector machine
Gillies, C.E., Otto, E.A., Vega-Warner, V. et al. BMC Bioinformatics (2016): 233 -
Quantifying RNA allelic ratios by microfluidic multiplex PCR and sequencing
Zhang, R., Li, X., Ramaswami, G. et al. Nature Methods (2014): 51–4 -
Don't put all your eggs in one basket: a cost-effective and powerful method to optimize primer choice for rRNA environmental community analyses using the Fluidigm Access Array.
Brown, S.P., Ferrer, A., Dalling, J.W., Heath, K.D. Molecular Ecology Resources (2016): doi: 10.1111/1755-0998.12507 -
Next Generation Sequencing for Clinical Diagnostics-Principles and Application to Targeted Resequencing for Hypertrophic Cardiomyopathy
Voelkerding, K.V., Dames, S., Durtschi, J.D. Journal of Molecular Diagnostics (2010): 539–51 -
A Microfluidic Device for Preparing Next Generation DNA Sequencing Libraries and for Automating Other Laboratory Protocols That Require One or More Column Chromatography Steps
Tan, S.J., Phan, H., Gerry, B.M., Kuhn, A., Hong, L.Z., Ong, Y.M., Poon, P.S.Y., Unger, M.A., Jones, R.C., Quake, S.R., Burkholder, W.F. PLoS One (2013): e64084 -
A long PCR–based approach for DNA enrichment prior to next-generation sequencing for systematic studies
Uribe-Convers, S., Duke, J.R., Moore, M.J., Tank, D.C. Applications in Plant Sciences (2014): 1,300,063 -
A Phylogenomic Approach Based on PCR Target Enrichment and High Throughput Sequencing: Resolving the Diversity within the South American Species of Bartsia L. (Orobanchaceae)
Uribe-Convers, S., Settles, M.L., Tank, D.C. PLoS One (2016): e0148203 -
Read count-based method for high-throughput allelic genotyping of transposable elements and structural variants
Kuhn, A., Ong, Y.M., Quake, S.R., Burkholder, W.F. BMC Genomics (2015): 508 -
Deconstructing the Polymerase Chain Reaction: Understanding and Correcting Bias Associated with Primer Degeneracies and Primer-Template Mismatches
Green, S.J., Venkatramanan, R., Naqib, A. PLoS One (2015): e0128122 -
Ion Torrent's Personal Genome Machine coupled with Fluidigm's Access Array Provides a Multiplexed Sample Approach to Rapid Evaluation of Novel Genomic Targets
Myers, J., Rothberg, J., May, A., Roberson, D. Journal of Biomolecular Techniques (2011): S39 -
High-Throughput Microfluidic Preparation of Targeted Resequencing Libraries Using the Access Array System
Anderson, M., Chen, P., Wang, J., Kaper, F., Lin, M., Pieprzyk, M., Jones. R. Journal of Biomolecular Techniques (2010): S26
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Primers for Castilleja and their utility across Orobanchaceae: II. Single-copy nuclear loci
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Microbiology/Pathogen Detection (viral)
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Great cormorants (Phalacrocorax carbo) as potential vectors for the dispersal of Vibrio cholerae
Laviad-Shitrit, S. Lev-Ari, T., Katzir, G. et al. Scientific Reports (2017): doi: 10.1038/s41598-017-08434-8 -
The Gut Microbiota of Healthy Chilean Subjects Reveals a High Abundance of the Phylum Verrucomicrobia
Frontiers in Microbiology (2017): 1,221 -
Detection of cytomegalovirus drug resistance mutations by next-generation sequencing
Sahoo, M.K., Lefterova, M.I., Yamamoto, F. et al. Journal of Clinical Microbiology (2013): 3,700–10 -
Microfluidic PCR combined with pyrosequencing for identification of allelic variants with phenotypic associations among targeted Salmonella genes
Yue, M., Schmieder, R., Edwards, R.A. et al. Applied and Environmental Microbiology (2012): 7,480–2 -
Relationship between nasopharyngeal and bronchoalveolar microbial communities in clinically healthy feedlot cattle
Zeineldin, M.M., Lowe, J.F., Grimmer, E.D. et al. BMC Microbiology (2017): 138 -
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